Individual differences in sleep Flashcards

1
Q

individual differences?

A

= factors which lead to variation in people
AGE - struggle initiating and maintaining sleep when older
GENDER - not much research
- hormonal changes eg. menstrual cycle
- pre-menopause = women appear to need more sleep (need same as men post-menopause)
CIRCADIAN RHYTHM - biological clock - linked to chronotype
GENETICS

there are overlaps, so don’t look at them in isolation

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2
Q

The components of sleep regulation

A

1) circadian clock located in the SCN tells us when its appropriate to go to sleep and when to wake up
- daily rhythms involve:
1) sleep
2) body temp (drops in by 1c in evening to fall asleep and increases by 1 degree in morning)
3) hormone secretion

2) sleep homeostasis = the longer you’ve been awake the more you need sleep
ALSO, pineal gland which produces melatonin (biological representation of dark) =secreted at night
–> also helps regulate body temp
(all work v closely together = v vulnerable to disruption)

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3
Q

Sleep across the lifespan

sleep latency def

wake after sleep onset

REM

SWS

Stage 1 +2

A

percentage of the time spent in each stage
sleep latency = time it takes to get to sleep –> not much difference, but takes infants slightly longer = could be due to environment etc
we also sleep onset latency increase slightly again in late adulthood and old age
WASO = wake after sleep onset
-children between 5 and 10 sleep through the night
- 45+ = no. of times you wake up increases (weak bladder/ medical problems)
REM
- 0-5 yr olds spend a lot more time in REM
- not much difference between infants
SWS
- decreases as you get older
-needed more when younger potentially due to development
- changes in brain structure means we struggle to initiate and maintain deep sleep when we’re older (less neurons)
(could be linked to WASO –> not in deep sleep = more likely to wake up)
stage 1 + 2
not much difference between all age groups

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4
Q

Sleep in newborns

A

newborns haven’t developed a regular circadian cycle (due to brain and visual system still developing)

  • sleep easily during the day and night
  • don’t respond to environmental cues (need light to reset cycles, but they don’t have this)
  • 16-18hrs per day
  • each episode usually 2 cycles (discontinuous sleep –> 2.5 -4 hours as they get hungry)
  • start cycles through REM
  • more time in SWS (esp. stage 3)
  • more REM
  • shorter cycles of around 50-60mins
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5
Q

Sleep in the first year

A

circadian rhythm arises around 2-3 months (start responding to environmental cues)

  • longer periods of sleep at night
  • sleep cycles more regular
  • sleep onset begins with NREM (go into stage 1 now)
  • spend a lot of time in SWS (developing still)
  • still more REM than adults
  • cycle : 50-60 mins
  • 6 months: sleep time reduces slightly and continuous sleep lengthens to around 6 hrs
  • 12 months: 14-15hrs sleep with most being at night with 1 or 2 naps a day
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6
Q

Sleep in young children (1-5)

A

sleep decreases as age increases due to physiological social changes (nursery/ school)
- REM decreases
- longer cycles
= more typical of adult
- consolidated sleep at night (some naps still)
- 3-5 yrs discontinue napping ( Jenni & Carskadon, 2000)

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7
Q

Daytime vs nightime sleep

A

young children sleep a lot during day and night

get older = day time sleep decreases

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8
Q

Teenagers

effect on performance?

A

a lot of changes in sleep patterns and behaviours (due to biological clock)

  • require 9-10hrs of sleep a night (Carskadon, 2003)
  • due to changes during puberty
  • delayed circadian rhythm due to changes in hormones (= sleep deprived lots due to school times) (delayed body clock) = go to bed much later in the evening (Waterhouse et al, 2012)
  • homeostatic drive for sleep too low in teens in early evening = can’t counteract circadian rhythm

Kelley et al, 2015

  • tested students at 10am and 2pm
  • 13-14 yr olds
    found: performed better in word pairs test later on (better in afternoon)
  • -> implications for later starting time at schools
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9
Q

Ideal sleep-wake cycle

other factors

A
  • get up around the same time every day
  • sleep around the same time every night

Other factors:

  • social life = stay up late
  • blue light from screens blocks melatonin = delays melatonin release
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10
Q

sleep in adults

A
- elderly tend to have:
delayed sleep onset
increased WASO/ fragmented sleep
early-morning awakening
decreased sleep stages 3 + 4
shorter REM
(decrease REM and SWS could explain memory problems)
frequent and shorter cycles
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11
Q

melatonin levels

young vs adults - differences in levels?

A
  • younger children show higher concentration of melatonin
  • older adults show very low levels of melatonin which could explain why they can’t maintain sleep during the night and often wake up
  • low melatonin in day, 10 oclock = increase melatonin
  • 5-10 yr olds have much larger increase than adults
  • concentration drops as we get older (explains problems initiating and maintaining sleep)
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12
Q

Chronotype preference

ages

gender differences?

A
chronotype changes with age
defo evening = 16-30
moderate evening = 31-41
intermediate = 42-58
moderate morning = 59-69
defo morning = 70-86
(teens = evening/ older adults = morning)
-- genetic basis to chronotype
-- gender differences? - men tend to go to bed later than women, but as we get older it tends to be around the same time
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13
Q

CLOCK genes

how many?

how do they work?

Period3?

% heritability?

A

chronotypes genetic basis

  • approximately 18 CLOCK genes identified as being critically important for this internal rhythm
  • they operate on a molecular feedback loop
  • genes are turned on and produce a message which produces clock proteins
  • these clock proteins work together, go into the nucleus + turn off their own genes = no more message = no more protein, protein degraded and then the whole thing repeats

so, there is a cycle of protein production and degradation
= this cycle provides the drive for circadian rhythm

one of the clock genes is Period3 - 2 forms:

1) homozygous PER3 5/5 = morning type
2) homozygous PER3 4/5 = evening type

morning/ eveningness estimated to be 50% heritable

morning types have shown increased slow wave activity at start of the night and also show greater deficits resulting from sleep deprivation

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14
Q

Morningness/ Eveningness

how do these types differ endogenously in the circadian phase of their biological clocks?

A
chronotype is linked to other biological processes that run on a 24hr cycle (circadian rhythm)
- morning and evening types differ endogenously in the circadian phase of their biological clocks
Morning type:
- temp decreases around 10pm
- increases in early hours of the morning (6am ish)
= in line with sleep wake cycle
- alertness peaks in the morning
Evening type:
- body temp decreases later 
- increases later in morning (8/9am ish)
- alertness peaks in the evening
(Kerkhof & Dongen, 1996)

-

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15
Q

effects of sleep deprivation on morning and evening types (Mane et al, 2014)

  • 2 measures used?
  • findings?
A

2 measures used:
- how easily they fall asleep unintentionally
- melatonin conc
found:
- morning have higher unintentional sleep than evening (overlaps with melatonin levels) (higher melatonin levels when falling asleep)
- sig difference in unintentional sleep episodes
dramatic increase in naps for morning types
(melatonin levels peak = unintentional sleep)
melatonin does increase for evening types too, but doesn’t result in naps as much
= morning types suffer more

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16
Q

Why do some people need more sleep?

A

linked to sleep homeostasis
- sleep pressure builds up = accumulation of adenosine
brain more active in day = more ATP used = more adenosine (measure of metabolic activity)
- adenosine builds up in prefrontal cortex = increase sleep pressure
(sleep duration related to build up of adenosine)
- more energy used = more adenosine
(people may respond to adenosine differently)