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Indications of FE Flashcards

1
Q

What most common defects for cardiac teratogens?

A

VSD

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2
Q

Risk percentage for fetal alcohol syndrome?

A

25-30%

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3
Q

Defects associated with alcohol?

A

ASD
AVSD
Coarctation of aorta
Dextrocardia
DORV
Interrupted AA
Pulmonic stenosis
TOF
VSD

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4
Q

Lithium is used for?

A

Bipolar (manic depression)

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5
Q

Risk percentage for Lithium? Most common associated defect?

A

10%
Ebstein’s

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6
Q

Defects for Lithium?

A

ASD
Dextrocardia
Mitral atresia
Tricuspid atresia

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7
Q

Valproic acid used for?

A

Anti-seizure medication used for epilepsy

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8
Q

Valproic acid cardiac defects?

A

Aortic stenosis
ASD
Coarctation of aorta
Interrupted AA
Left ventricular hypoplasia
Pulmonary atresia
TOF
VSD

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9
Q

Retinoic acid used for?

A

treatment of acne

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10
Q

What is the risk percentage of retinoic acid (Accutane)?

A

3.6%

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11
Q

Associated defects for retinoic acid?

A

Coarctation of aorta
DORV (conotruncal defects)
Interrupted AA
Pulmonary atresia
TOF
Tricuspid atresia
VSD

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12
Q

Hydantoin (Dilantin) used for?

A

Anti-convulsant medication used to treat seizure disorder

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13
Q

Risk percentage for Hydantoin?

A

2-3%

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14
Q

Cardiac defects for Hydantoin?

A

Aortic stenosis
ASD
Coarctation of aorta
Interrupted AA
Pulmonic stenosis
VSD

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15
Q

Trimethadione used for?

A

Treat seizure disorder

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16
Q

Risk percentage Trimethadione?

A

15-30%

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17
Q

Cardiac defects for Trimethadione?

A

aortic stenosis
ASD
DORV
HLHS
pulmonic stenosis
TOF
TGA
VSD

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18
Q

What medication was discontinued in the 1960?

A

Thalidomide

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19
Q

Risk percentage of Thalidomide?

20
Q

Cardiac defects associated with Thalidomine?

A

ASD
DORV
Pulmonary atresia
TGA
TOF
Tricuspid atresia
VSD

21
Q

What is chemically related to retinoic acid?

22
Q

What is Phenylketonuria?

A

genetic disorder
inability of the body to utilize phenylalanine (essential amino acid)

23
Q

Risk percentage of PKU?

24
Q

What is the most common defect associated with PKU?

A

TOF
25-50% of cases

25
Q

What defects are also associated with PKU?

26
Q

Risk percentage of heart defects with a diabetic mother?

27
Q

What are the most common cardiac defects of mother with diabetes?

A

VSD
TGA
Aortic stenosis

Also:
truncus arteriosus
DORV

28
Q

Most common heart condition of diabetic mothers?

A

Hypertrophic cardiomyopathy

29
Q

Percentage of hypertrophic cardiomyopathy?
Percentage of hypertrophic cardiomyopathy will result in congestive heart failure?

A

Up to 30%
12%

30
Q

When does rubella syndrome occur?

A

In babies whose mother have Rubella (German measles) during pregnancy.

The risk does decrease with GA. Highest in the first trimester.

31
Q

Risk percentage of rubella syndrome?

31
Q

What is the most common cardiac abnormality of Rubella?

A

Patent ductus arteriosus (the fetal ductus arteriosus does not close spontaneously after birth)

31
Q

What other defects are associated with Rubella?

A

ASD
Peripheral pulmonary stenosis (branch stenosis)
Pulmonary valvular stenosis
VSD

32
Q

Babies with rubella also have?

A

cataracts
nerve deafness
microcephaly
mental deficiency

33
Q

Why can’t pregnant patient take Ibprofen?

A

Potential to cause premature constriction of the ductus arteriosus

34
Q

CHD in live births?

A

2-6.5 out 1000 live births

35
Q

If bicuspid aorta included?

A

Increase to 10 out 1000 live births

36
Q

If PDA not included?

A

Decreases to 3.7 out 1000 live births

37
Q

When is NT measured?

A

11-14 weeks

38
Q

Increased thickness means what?

A

Fetus is at risk for chromosomal disorders and congenital defects

39
Q

What are the chromosomal anomalies for increased NT?

A

Trisomy 21
Trisomy 18
Trisomy 13
Turners syndrome (45XO)

40
Q

Normal karyotype but increased thickness, what other abnormalities?

A

heart defects
CHD
abdominal wall defects

41
Q

Percentage of fetus with congenital heart disease will have extracardiac abnormalities?

42
Q

If there is a major fetal extracardiac abnormality and a chromosomal abnormality, percentage increases to?

Indications of FE (1 decks)

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