Indications for Androgens Flashcards

1
Q

what are the main indications for HRT?

A

delayed puberty, aging men, primary or secondary hypogonadism

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2
Q

what are androgens capable of restoring, what is one function that they cannot achieve alone?

A

they can induce secondary sexual characteristics, restore sexual function in the aging but they cannot induce spermatogenesis (need hCG to provoke FSH release and high local T levels)

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3
Q

anabolic effects of androgens?

A

nitrogen retention and muscle mass increases in those with wasting syndromes (AIDS) and hypogonadism

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4
Q

what is the most effective androgen for PED?

A

nandrolone

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5
Q

what are two OTC formulations that are risky at best?

A

Androstenedione (banned in 2004)

DHEA dehydroepiandrosterone

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6
Q

OB/GYN uses for E2 agonist, danazol

A

excess danazol will feedback suppress estrogen release in endometriosis

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7
Q

what’s a drug that combines esterified estrogens and T for women

A

estratest, for libido? Looks like HRT during menopause according to the internet

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