Incontinence Flashcards

1
Q

What major complication of incontinence are we so concerned about in the elderly?

A

FALLS

patients rushing to reach the toilet on time, and problematic if pt PU before reaching the toilet

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2
Q

how does prevalence of incontinence vary between men and women?

A

prevalence in men usually half that in women

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3
Q

examples of LUTS?

A

frequency
urgency
nocturia-need to pass urine during the night which wakens one from sleep and is an independent RF for falls
incontinence

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4
Q

define overactive bladder

A

syndrome including urinary urgency with or without urge incontinence, which is usually accompanied by frequency (voiding 8 or more times/24hr) and nocturia
can be associated with detrusor overactivity.

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5
Q

what is stress incontinence?

A

involuntary leakage of urine caused by failure for bladder outlet to remain closed during rises in intra-abdominal pressure

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6
Q

how is a diagnosis of detrusor overactivity confirmed?

A

requires urodynamic studies

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7
Q

what diagnosis does the following correspond to: spontaneous bladder contraction during filling as pt attempts to prevent micturition?

A

detrusor overactivity

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8
Q

what is nocturnal polyuria?

A

passing more than 1/3 of your urine volume during the night

can be identified by viewing frequency volume charts

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9
Q

types of urinary incontinence?

A

stress-result of weakness of the urinary outlet so fails to remain closed during rises in intra-abdo pressure e.g. coughing, laughing
urge-high bladder pressure causes bladder to fail in storing urine
overflow-bladder overfull due to bladder outlet obstruction e.g. BPH, so overflows
mixed-combination of stress and urge
functional-incontinence due to more general impairment e.g. cognitive-e.g. pt with dementia who has frontal cortex dysfunction so makes no attempt to move to the toilet before micturition, functional, affective, pt unable to get to the bathroom on time.
fistulae e.g. in crohns

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10
Q

what is necessary for the process of micturition?

A

there must be voluntary relaxation of the striated muscle around the urethra to reduce urethral pressure (pelvic floor muscles already not functioning adequately in stress incontinence) AND
corresponding increase in bladder pressure due to detrusor contraction-M3 muscarinic receptors stimulated by PNS

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11
Q

normal bladder capacity, and what volume causes a desire to void?

A

around 600ml

desire to void usually felt at around 250ml

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12
Q

primary muscle for inhibiting the release of urine?

A

internal urethral sphincter-smooth muscle, continuation of detrusor muscle, under autonomic (involuntary) control

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13
Q

how is detrusor contraction coordinated with urethral relaxation to allow micturition to take place?

A

by the pontine micturition centre in the midbrain

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14
Q

overview of how micturition is stimulated following bladder filling?

A

filling causes detrusor muscle of the bladder to stretch-increased signals sent to the sacral region, which then causes PNS stimulation of the detrusor via the pelvic nerves (S2-S4) to contract. stretching bladder also causes increased signals to be sent up to the brain, where the pontine micturition centre coordinates detrusor contraction with urethral relaxation-brain decreases APs in somatic motor neurones to the external urethral sphincter (pudendal nerve S2-S4).
if voiding not desired, inhibitor signals sent from the brain to the detrusor muscle (hypogastric nerve T10-L2 SNS).

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15
Q

most common cause of stress incontinence in men?

A

prostate damage, usually post-op following prostatectomy

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16
Q

structure most important for stopping stress incontinence in women?

A

peri-urethral striated muscle

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17
Q

useful questions for assessing urinary incontinence?

A

any problems with your bladder or bowels?
do you ever leak urine?
do you find it difficult to hold urine when you feel the urge to go?
do you have a problem with going to the toilet too often to pass urine during the day?
do you have to wake from sleep at night to pass urine?

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18
Q

storage symptoms?

A
frequency of micturition
urgency of micturition
continual urine loss
nocturia
urge incontinence
stress incontinence
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19
Q

voiding symptoms?

A

terminal dribble
hesitancy
intermittent stream
incomplete emptying

20
Q

what should be asked about in the social history which can exacerbate incontinence?

A

smoking
alcohol
caffeine
fluid intake

21
Q

complications of incontinence for the patient?

A
social isolation
admission to care home
falls
pressure ulcers
skin infection
impaired QOL
depression
22
Q

what co-morbidities might incontinence be a consequence of?

A

dementia-frontal lobe dysfunction-pt doesn’t make attempt to go to the toilet before micturition, plus lack of function of the micturition inhibitory centre.
MSK disease-pt unable to mobilise well enough to access the toilet
chronic lung disease
CCF-causes surges in BNP, commonly assoc. with nocturia, plux tx diuretics-exacerbate all types of incontinence, +ACEIs-bradykinin induced cough exacerbates incontinence.
MS
stroke
DM
parkinson’s disease

23
Q

what examination must NOT be missed in assessing pt with urinary incontinence?

A

DRE:
assess anal tone
constipation, rectal mass
prostate size and consistency

24
Q

simple investigations for the assessment of incontinence?

A

-frequency-volume charts-ask pt to complete diary over 3 day period that records fluid intake, volume of urine passed and episodes of incontinence
-urinalysis-dipstick-glucose, proteinuria-primary kidney pathology, nitrites+leucocytes-infection, haematuria
plus M, C+S
-bloods-FBC, U+Es, Ca2+-hypercalcaemia can cause constipation and confusion, glucose
-imaging-post void bladder scan-rule out chronic urinary retention
others depending on specific indications:
USS Abdo if CKD-evaluate kidney size and look for signs of obstructive uropathy
CT urography-renal stones
CT abdo
IV urogram

25
Q

what trend from a frequency volume chart is suggestive of an overactive bladder?

A

frequent small volumes of urine being passed

26
Q

what is uroflowmetry?

A

an example of a urodynamic study, which measures the urinary flow rate, and is useful for diagnosing bladder outlet obstruction e.g. BPH
usually pt left to void in private and the commode has a rotating disc-inertia increased as urine falls onto it, which can be measured by the computer and translated into a flow rate.
normal results: total voided volume more than 200ml, flow time 15-20s, Qmax more than 20mls/s, smooth parabolic curve.

27
Q

uroflowmetry trace for a pt with bladder outflow obstruction?

A

prolonged flow rate with low Qmax

28
Q

most important imaging investigation for urinary incontinence?

A

post void bladder scan

29
Q

what is cystometry?

A

bladder pressure studies:
bladder filled with saline at room temp via small bore urethral catheter passed along with a pressure transducer, and further pressure transducer placed in rectum. pressure recordings measured as bladder filled.
combined with radiographic imaging=videourodynamics

30
Q

how is true intravesical pressure measured with pressure urodynamics?

A

intravesical pressure minus intra abdominal pressure/rectal pressure (measured via rectal transducer)

31
Q

uroflowmetry features of an overactive bladder?

A

decreased time to maximum flow, increased max flow rate and decreased max flow

32
Q

define polyuria

A

more than 2.5L urine passed/24hrs

33
Q

what might cause stress incontinence in men?

A

prostatectomy

prostate essential to bladder outlet integrity in men

34
Q

transient reversible causes of urinary incontinence?

A
DIAPPERS:
delirium
infection
atrophy-vaginal-trial topical oestrogens
pharmacological
psychological-dementia, delirium
excess urine-DM, DI, psychogenic polydipsia
reduced mobility
stool impaction (constipation)-do DRE!
35
Q

RFs for stress incontinence?

A

females: outlet already weaker due to shorter urethra and absence of prostate, childbirth-nerve and ligament damage, obesity-increased strain and weakening of pelvic floor
surgery: hysterectomy, TURP
increasing age
neurological disease
urinary infection
post menopausal-oestrogen loss
bladder outlet obstruction

36
Q

causes of overactive bladder (urge incontinence)?

A

idiopathic
neurogenic-MS, stroke or SC injury, parkinsonism
infective-UTI
bladder outlet obstruction

37
Q

causes of bladder outlet obstruction?

A
BPH
malignancy-prostate or bladder, or carcinoma of the cervix or colon
calculi
blood clot
trauma
STDs, part. in women
phimosis
stricture (male preponderance)
38
Q

why might BPH be a contributer to urge incontinence?

A

BPH causes bladder outlet obstruction and can cause overflow incontinence, but over time, there is a strain on the bladder which causes residual urine to be left which irritates the bladder and can cause detrusor overactivity.

39
Q

drugs which may cause/worsen urinary incontinence?

A

anticholinergics-cause urinary retention
opioids-cause urinary retention by causing constipation
cholinesterase inhibitors-increase bladder contraction-increased ACh acting on M3
ACEI-bradykinin induced cough
alpha blockers-relax bladder outlet
alpha agonists-urinary retention
hypnotics-reduced awareness of need to urinate
haloperidol-anticholinergic, may cause retention
Ca2+ channel blockers-decrease smooth muscle contractility

40
Q

pt education to manage stress incontinence?

A

smoking cessation
reduce alcohol and caffeine
lose weight
manage constipation-increase fibre in diet

41
Q

non-pharmacological management of stress incontinence?

A

pelvic floor exercises-advice can be given by physiotherapists and continence advisors
pudendal nerve stimulation if initial pelvic floor muscle contraction weak
vaginal cones-must contract pelvic floor muscles to keep cone in place

42
Q

medical and surgical management of stress incontinence?

A

duloxetine-SNRI, thought to increase urethral sphincter tone during bladder filling
surgical: mid-urethral sling insertion (tension free vaginal tape) provides support under urethra
colposuspension-much more invasive
injection of bulking agents into the urethra e.g. silicone

43
Q

pt education to manage an overactive bladder (urge incontinence)?

A

reduce fluid intake, especially in the evening
reduce alcohol and caffeine
lose weight
manage constipation

44
Q

non-pharmacological management of an overactive bladder?

A

pt education e.g. reduce fluid intake
community continence advisor-can assess pt in own home and give advice
behavioural therapy-bladder retraining-this should be 1st line for at least 6 wks alongside pelvic floor muscle exercises. bladder retraining involves increasing the time between 1st desire to void and voiding.
complementary therapy

45
Q

medical and surgical management of overactive bladder?

A

antimuscarinics e.g. oxybutynin
vaginal oestrogens for those with vaginal atrophy
botulinum toxin injected via cystoscopy to inhibit NT release hence decrease contractility

surgical: sacral nerve stimulation

46
Q

urinary catheter least associated with infection?

A

low friction intermittent catheter

47
Q

what 2 diagnoses is the failure to produce urine indicative of?

A

acute urinary retention or AKI

need catheter insertion