Incontinence Flashcards

1
Q

What is the MOST likely side effect after Botox procedure for treatment of overactive bladder?

A

Urinary Tract Infection

Risk of UTI = 33%

Risk of voiding dysfunction that requires catheterization is only 5%

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2
Q

In an obese woman what is the risk of developing urinary incontinence?

A

GREATER than 50%!!!

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3
Q

What are the 5 key components of a workup for urinary incontinence?

A
  1. H&P
  2. Cough stress test
  3. PVR
  4. Assessment urethral mobility
  5. UA & UC
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4
Q

At what amount of RBC’s on microscopic UA do ACOG and AUGS recommend eval for microscopic hematuria?

A

Greater than 25 RBCs per hpf

  • This is only true for asymptomatic, low risk, non-smoking women age 35-50
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4
Q

What is the Q tip test?

A

using q-tip (or straight cath) to assess movement of urethra with Valsalva. Positive is > 30 degrees above the horizontal

The prescence of urethral mobility indicates uncomplicated SUI (lack of urethral mobility is associated with a 2 fold increase in failure rate of mid urethral sling

Patient who lack urethral mobility may be better candidates for urethral bulking agents rather than sling

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5
Q

What is a normal bladder capacity?
What about a normal PVR?

A

capacity 350 cc
PVR less than 150 cc

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6
Q

What is the mechanism of action of oxybutynin?

A

Anti muscarinic, blocks M2/M3

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7
Q

Side effects of anti muscarinics?

A

dry mouth
dry eyes
constipation

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8
Q

Contraindications to anti-muscarinics?

A

Narrow angle glaucoma
Urinary retention
Gastric retention

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9
Q

Mechanism of Mirabegron?

A

Beta 3 agonist

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10
Q

Side effects of Mirabegron?

A

Diarrhea
Tachycardia
Headache

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11
Q

When should Mirabegon be avoided?

A

Uncontrolled HTN, renal or liver disease

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12
Q

What is an abnormal post void residual?

A

> 150 cc

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13
Q

Basic Eval of urinary incontinence

A

History/Bladder Diary
Physical
- Assess for prolapse
- Assess estrogen status
Cough test to observe leakage
Q-tip test to assess urethral hyper mobility
Post void residual
UA/UCx

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14
Q

First line treatment for Urge Incontinence

A

Behavioral!

Weight loss
Avoiding bladder irritants
Fluid management
Bladder re-training
Timed Voiding
Pelvic Floor Physical Therapy

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15
Q

Second line treatment for Urge Incontinence?

A

Pharmacologic!

B-3 agonists (mirabegron)
Anti-muscarinics (oxybutinin)
Vaginal estrogen
Botox injection

THEN
Interstim (sacral neuromodulation)

16
Q

Surgical management of stress urinary incontience?

A

Retropubic midurethal slings (tension-free vaginal tape)
Inserted through the retropubic space and exit through the abdominal in the suprapubic area

  • Local, regional or GETA
  • Dorsal lithotomy
  • Mark abdominal incisions, 2 cm lateral to the midline
  • Hydrodissection - inject into the vaginal wall inferior and lateral to the urethra in addition to downward along the back of the pubi bone to the retropubic space
  • Allis clamp at 1 cm proximal to the urethral meatus, about 1.5 cm in legnth to accomodate the sling
  • Allis clamps moved to lateral edges of mucosa to retract laterally
  • Minimal dissection lateral to the midurethra, between the vaginal mucosa and the pubocervical fasica is performed bilaterally with Metz
  • Catheter guide placed, and bladder deviated to opposite side of trocar insertion
  • Insert trocar lateral to the urethra, pass the trocar behind pubic symphysis and exit through the abdominal sites.
  • Aim trocar handle in the direction of the outer aspect of patient’s shoulder
  • Cystoscopy, if bladder perforation, remove and re-do
  • To ensure tension-free sling, 7 mm heegar dilator placed between sling and urethra (should not compress urethra at rest)
  • Remove the plastic sheaths, trim mesh at abdmoinal insicisons
  • Voiding trial before discharge

**Deviation of the trocar in a cephalad direction may result in injury to bowel, bladder, blood vessels
**Deviation laterally could injury major vasculature (external illiac vessel, obturator vessels, epigastric vessels)

17
Q

Possible complications of mid-urethral sling?

A

Failure/ persistent SUI (5%)
90% dry, 95% happy, 5% unchanged

Urinary retention (1/4 of pts)

Infection (15%)

Bleeding (2%)
- surgical site
- hematoma in space of retzius

Injury to near by structures
- Bladder injury with suture/mesh (3%)
- Ureteral injury (< 2%)
- Bowel injury (exceedingly rare < .5%)

Mesh exposure (< 2%)

18
Q

When is mesh ok to use in pelvic surgery?

A

Insertion of mid urethral sling
Sacrocolpoexy

19
Q

Differences between retropubic sling and transobturator sling?

A

Retropubic - higher efficacy, slightly increased risk of bladder perforation, bowel injury, short-term pubic pain, and post op voiding dysfunction

Transobturator - lower efficacy, lower risk of adverse events, more short term pain but less voiding dysfunction, go through obturator foramen

20
Q

What is the sling made of?

A

Type 1 polypropylene mesh

21
Q

Contraindications to mid urethral sling?

A

Current UTI
Current pregnancy
Anticoagulation
Previous surgeries in the path of sling placement (vascular graft, bowel, transplant kidney)