Inclusion bodies Flashcards

1
Q

unwanted materials inside RBCs, formed due to improper/ incomplete development or
maturation of cells

A

Inclusion bodies

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2
Q

–fragments of the nucleus resulting from karyorrhexis, nuclear remnants of DNA

A

Howell- Jolly bodies

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3
Q

the most specific reaction for DNA, Howell - Jolly bodies

A

Feulgen stain

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4
Q

– formed because of precipitation of ribosomes and RNA due to heavy metal poisoning

A

Basophilic Stipplings

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5
Q

because of polychromasia/polychromatophilia (: reticulocytes [remnants of
RNA])

A

Fine Basophilic Stippling

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6
Q

problem in hemoglobin synthesis (eg. if a px is intoxicated with lead

A

Coarse Basophilic Stippling

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7
Q

remnants of microtubules and mitotic spindle [bell shape, hat shape in electron microscopy]

A

Cabot Ring

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8
Q

formed because of oxidative stress, results to the denaturation of the hgb. (eg. G6PD deficiency,
thalassemia, hemoglobinopathy)

A

Heinz Bodies

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9
Q

Stained used in Heinz Bodies

A

Supravital stain

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10
Q

spleen removed the Heinz Bodies in the red cell

A

Bite cell (Degmacyte)

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11
Q

– problem with globin, associated w/ thalassemia (Supravital stain)

A

Hemoglobin H inclusion

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12
Q

accumulation of iron deposits (eg. intoxicated with lead)

A

Ringed sideroblast -

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12
Q

changes in structure of hgb, “bar of gold”

A

Hb CC crystals

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13
Q

Washington monument shaped like crystal

A

Hb SC crystals

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14
Q

confirm the presence of iron

  • ringed sideroblast stain
A

Prussian blue (Perl’s stain)

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15
Q

– basophilic inclusions aggregates near the periphery of cell
o Formed because of the accumulation of ribosomes, mitochondria, and unused iron

A

Pappenheimer bodies

16
Q

tick borne, Maltese cross-formation

A

Babesia

17
Q

Because of antibodies (can be cold agglutinins, significant hemolytic anemia, or pneumonia)

A

Agglutination

18
Q

increase plasma proteins, stack of coins (presence of inflammation), seen in multiple myeloma

A

Rouleaux