In Utero Flashcards
When you were a twinkle in your mother’s eye…
- Development trajectories started before you were even a thought
- Epigenetics (you are older than you think)
- Maternal behaviours had an impact on you
Conception: The First Stage
- Age of conception is getting higher in Canada
- Rates of triplets, quadruplets and quintuplets has increased over 230% since the mid 1990s
Advanced Maternal Age (AMA)
- Increased AMA leads to an increase in conception of multiple births, and an increase in the use of assisted human reproductive techniques
- Fertility drugs-> assisted reproductive techniques
- Cryopreservation-> freezes the embryos created in IVF
- Benefit package in Silicon Valley-> young women= prime age to work
- Artificial Insemination-> injects sperm directly into a woman’s uterus
- Age and reproductive techniques lead to multiple births
Antenatal
conception-> postpartum
-6-8 weeks after you’ve had the baby (under the care of an obstetrician or midwife)
Pregnancy
physical condition in which a woman’s body is nurturing a developing embryo or fetus (40 weeks)
-4-5 weeks pregnant before you realize that you’re pregnant (factors into the 40 weeks)
Prenatal
- process that transforms a zygote into a newborn
- Determine when it acc applies
1st Trimester
- from the zygote implantation to 12 weeks
- Most at risk for miscarriage
2nd Trimester
12-24 weeks
- begin to feel movement of the baby
- when everything develops
3rd Trimester
25+ weeks
- Increased emotional attachment to the fetus
- Realize that the fetus is coming
Key issues in 1st Trimester
- Ectopic pregnancy-> implants outside the uterus
- Abnormal urine & blood tests
- Normal bleeding in the first trimester
- Miscarriage
- Malnutrition-> why is it a Canadian issue?
- Lower SES countries
- Could be quality of food
- Morning sickness and hyperemesis (morning sickness on steroid-> vomiting throughout the pregnancy, hospitalized as they attain nothing)
- 1 in 50 women
- Kate Middleton suffered with it: reshaped the way that we think of pregnancy
Key issues in 2nd Trimester
- Gestational diabetes-> baby gains too much weight (hard delivery)
- Screening test (drinking sugary syrup and tests how your body absorbs it)
- Improved diet and exercise (intervention is nothing compared to the screening for it)
- Excessive weight gain
- Rh incompatibility of mother (blood types don’t match and mom’s body attacks it)
- Miscarriage= 13-20 weeks
- Premature labour= 21+ weeks (broad spectrums in medicine)
Key issues in 3rd Trimester
o Increased BP
o Bleeding
-Premature labour
-Bladder infection-> asymptomatic
-Toxemia-> pre-eclampsia (Eclampsia= pre-eclampsia + seizures)
-After 20 weeks gestation
-6 weeks after delivery (naturally dissipates over time)
-Hypertension & proteinuria
-Swelling, blurred visions, headaches
-Treat it by delivering the baby and the placenta (baby needs to reach that viability)
-Managing the health of the baby and the mother
-Development of an abnormal placenta
Obsession with Growth
-Compare babies to the size of fruit
What is Normal during Pregnancy… Everything and Anything (mostly)
- Not many studies to see what is normal during pregnancy?
- Feet grow, hair falls out/ stays in
- Paradoxes are normal
Ethical debate of when to intervene
- e.g. thalidomide case preventing morning sickness
- Crossed the placental barrier and effect the baby
- We don’t have a good understanding of development (leave it alone?)
- Risk vs benefits (health of fetus and woman)
Age of viability in London, ON
24 weeks
viability at 23 weeks
17%
viability at 24 weeks
39%
viability at 25 weeks
50%
viability at 26 weeks
80%
viability at 27 weeks
90%
viability at 28-31 weeks
90-95%
viability at 32-33 weeks
95%
viability at 34+ weeks
100%
Age of Viability Stats
o Age of viability is decreasing as medicine is increasing
- Repercussion of lowering the age-> use a lot of resources on 1 person ($$$), implications for abortion, survival rate doesn’t mean that it will be developed like a full-term baby (intellectual and developmental delay)
- Increased rate of children with medical complexity
- Technology dependant
- 2 or more underdeveloped organs