Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Endocrine Pharmacology > Immunosuppressive Drugs > Flashcards

Immunosuppressive Drugs Flashcards

1
Q

Bind with cyclophilin

A

Cyclosporine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Inhibit calcineurin and inhibit activating T cells

A

Cyclosporine
Tacrolimus ( FK506)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Used in ocular graft versus host disease

A

Cyclosporine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adverse effects of cyclosporine and tacrolimus
3 toxicity
4 Hyper

A

Nephrotoxicity
Hepatotoxicity
Bone marrow toxicity

Hyper tension
Hyperglycemia
HyperKalemia
HyperTricosis

Seizures
Inc incidence of lymphoma and other cancers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Induce tumor growth factor

A

Cyclosporine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Bind to immunophilin FK binding protein

A

Tacrolimus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

More potent that cyclosporine by 10-100 times

A

Tacrolimus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

From group of cytotoxic immunosuppressive

A

Azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Inhibit both de Novo pathway and salvage pathway

A

Azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Interferes with purine nucleic acid metabolism and stops lymphoid cell proliferation

A

Azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

It’s adverse effects are bone marrow suppression and hepatic dysfunction

A

Azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Inhibit de Novo synthesis of purines

A

Mycophenolate mofetil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Used in acute and chronic graft versus host disease in hematopoietic stem cell transplantation

A

Mycophenolate mofetil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Used in cardiac transplantation

A

Mycophenolate mofetil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

It’s side effects are hypertension and myelosuppresion

A

Mycophenolate mofetil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Is an anti TNF alpha MABs

A

Infliximab

17
Q

Is an anti Ig-E

A

Omalizumab

18
Q

Used in refractory Bronchial asthma

A

Omalizumab

19
Q

From adverse effects of The (D) immune globulin

A

Fever
Local discomfort

20
Q

Cyclosporine inhibits which type of cell

A

T lymphocyte proliferation

Endocrine Pharmacology (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions