Immunosuppresive Agents

Question 1

Which agents cause destruction of t-lymphocytes?

Answer 1

Antithymocyte globulin

Muromonab-CD3

Question 2

Which agents block calcineurin and inhibit IL-2 synthesis?

Answer 2

Cyclosporine

Tacrolimus

Question 3

Which agents block IL-2 receptor?

Answer 3

Basiliximab

Question 4

Which agents block cytokine-stimulated cell proliferation?

Answer 4

Sirolimus

Everolimus

Question 5

Which agents inhibit purine synthesis?

Answer 5

Azathioprine

Mycophenolate mofetil

Question 6

Moa of basiliximab?

Answer 6

Blocks il-2 receptor

Question 7

Moa of antithymocyte globulins?

Answer 7

Destruction of t lymphocytes

Question 8

Moa of sirolimus?

Answer 8

Blocks cytokine stimulated cell proliferation

Question 9

Moa of muromonab-cd3?

Answer 9

Destruction of t lymphocytes

Question 10

Moa of azathioprine?

Answer 10

Inhibits purine synthesis

Question 11

Moa of tacrolimus?

Answer 11

Blocks calcineurin and inhibits il-2 synthesis

Question 12

Moa of mycophenolate mofetil?

Answer 12

Inhibits purine synthesis

Question 13

Moa of cyclosporine?

Answer 13

Blocks calcineurin and inhibits il-2 synthesis

Question 14

Moa of everolimus?

Answer 14

Blocks cytokine stimulated cell proliferation