Immunopathology Week 2 - Tut Questions

Question 1

Name 6 factors which can influence the impact of stressors on cells and tissues

Answer 1

1. The type of injury
2. The duration of injury
3. The severity of injury
4. The type of cell/tissue being injured
5. The current status of the tissue
6. The adaptability of the tissue

Question 2

Name the cell structures and processes which are most vulnerable to injury.

Answer 2

Directly damaging proteins, membranes, DNA and other structures

Mitochondrial damage causing ATP depletion

Increasing intracellular calcium

Damaging plasma membranes and lysosomal membranes

Forming free radicals - These are atoms or molecules with an unpaired electron, thus unstable.

Question 3

State if the following are True or False:

Ischaemia can cause hypoxia or anoxia

Hypoxia generally results in hypoxaemia

Ischaemia and hypoxaemia need to both occur in order to cause tissue hypoxia.

Ischaemia can cause infarction

Necrotic tissue which occurs as a consequence of ischaemia is called an infarct.

Answer 3

Ischaemia can cause hypoxia or anoxia - True

Hypoxia generally results in hypoxaemia – False

Ischaemia and hypoxaemia need to both occur in order to cause tissue hypoxia. - False

Ischaemia can cause infarction - True

Necrotic tissue which occurs as a consequence of ischaemia is called an infarct. - True