Immunopathology- Autoinflammation and Autoimmunity Flashcards
1
Q
what is IBS?
A
Inflammatory bowel disease is a chronic inflammatory condition resulting from inappropriate activation of an immune response within the gastrointestinal mucosa
2
Q
what are the features of Crohn’s disease?
A
- Inflammatory cells and fibrosis throughout all layers of the bowel wall
- affect bowel can be interspersed with normal bowel (skip lesions)
- Granulomas
3
Q
what are the features of Ulcerative colitis?
A
Restricted to the intestinal mucosa
extending through the rectum and colon.
- Pseudopolyps
Can become toxic mega colon
4
Q
how accurate should a pipette be?
A
+/- 1% standard devation
5
Q
what is the inflammation of crohns disease?
A
through the GI tract
6
Q
what is the inflammation of ulcerative colitis?
A
only in the rectum and colon
7
Q
what is the microbiota of crohns disease?
A
much higher levels of bacteria than normal
8
Q
what is the microbiota of ulcerative colitis?
A
Much lover levels of bacteria than normal
