Immunopathologies Flashcards
1
Q
type II:
define, mechanisms(3),
A
-antibody causing harm to self (often autoantibodies), also includes auto-reactive antibody against surface receptors, which stimulate the cell.
- neutralization
- complement-mediated damage
- stimulatory hypersensitivity
2
Q
type II:
diseases(8)
A
- Myasthenia Gravis
- Goodpasture Syndrome
- Dressler Syndrome
- Rheumatic Heart Disease
- Autoimmune Thrombocytopenic Purpura (ATP)
- Autoimmune Hemolytic Anemia (AIHA)
- Gaves Disease
- Hashimoto Disease
3
Q
type II:
etiology(7)
A
- hybrid antigen formation []
- forbidden clone emergence []
- cross rxn btwne foreign & self antigens []
- passive antibody []
- innocent bystander []
- seqestered antigen release []
- regulatory mechanism failures []
4
Q
type II:
diagnosis
A
-immunofluorescence [
