Immunology Part 2: Immunopathology Flashcards
What is transplantation?
Taking cells, tissues, or organs from one person and placing them in another
What is an allograft?
A graft that is from one person to another
What is an autograft?
A graft taken from one part of a person’s body and placed into a different location in that same individuals body
What is a donor and a graft?
A donor is the person providing the graft and a recipient is the person receiving the graft
How does the immune system react to organ transplantation?
As if the organ is a pathogen
Rejection results in a ___ that damages the transplanted tissues
inflammatory response
Which area of the immune system mediates graft rejection?
adaptive immune system because it shows specificity and memory and depends on lymphocytes
What molecules interact for a T lymphocyte to recognize a graft as self?
MHC and HLAs
Transfusion reactions can occur if the blood a person receives has different ___ than their own
antigens
What are ABO antigens?
Carbohydrate antigens linked to cells surface proteins and lipids found on red blood cells
What are the 2 types of antigens on red blood cells?
A and B
ABO blood groups are ___ determined?
genetically
If you have A antigens, what type of blood do you have? B? A and B? No A or B?
A, B, AB, O
Do you have to be exposed to a different blood group antigen to make antibodies against it?
No
If you have type A blood, what antibodies will you have? If you have type B blood, what antibodies will you have?
What about type AB or O?
Anti-B, Anti-A, none, anti-a and anti-b
