immunology intro Flashcards

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1
Q

immune cells

A

derived from haematopoetic stem cells in bone marrow
lymphoid cells - T and b cells
myeloid cells - DCs, mast cells, RBCs, neutrophil

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2
Q

inflammation

A

recruitment/accumulation of fluid, plasma proteins and leukocytes initiated by trauma or infection

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3
Q

CD4 cells

A

determine direction of immune response by secreting cytokines

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4
Q

Th1

A

IFNy
intracellular
autoimmunity

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5
Q

Th2

A
IL-4 drives differentiation
secretes Il-4, IL-5
extracellular
parasites
allergy
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6
Q

Th17

A

TNFB and IL-6 drive differentiation
secrete Il-17, IL-22
inflammatory

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7
Q

Treg

A

immune suppression

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