immunology basics

Question 1

what cells does the erythoid lineage produce?

Answer 1

erythrocytes and megakaryocytes

Question 2

what cells does the myeloid lineage produce?

Answer 2

monocytes, macrophages and dendritic cells

Question 3

what cells does the lymphoid lineage produce?

Answer 3

small and large lymphocytes

Question 4

what cells are in the myeloid lineage?

Answer 4

neutrophils, eosinophils, basophils, monocytes, macrophages, dendritic cells and mast cells

Question 5

what cells are PMNs and granulocytes?

Answer 5

neutrophils, eosinophils and basophils

Question 6

neutrophils

Answer 6

phagocyte of innate immunity

Question 7

eosinophils

Answer 7

defend against parasites

Question 8

basophils

Answer 8

defend against parasites , rare

Question 9

monocytes

Answer 9

precursor of a macrophage

Question 10

macrophage

Answer 10

differentiated monocyte, phagocyte, innate and adaptive immunity

Question 11

dendritic cells

Answer 11

antigen presenting to T lymphocytes

Question 12

mast cells

Answer 12

responsible for allergy responses and initial immune response

Question 13

what cells are in the lymphoid lineage?

Answer 13

large lymphocytes and small lymphocytes

Question 14

large lymphocytes

Answer 14

natural killer cells, viral infections and ADCC

Question 15

small lymphocytes

Answer 15

B cells and T cells

Question 16

cytokines

Answer 16

glycoproteins involved in cell signalling

Question 17

chemokines

Answer 17

cell migration

Question 18

interlukins

Answer 18

type of cytokine, cell communication

Question 19

interferons

Answer 19

effects viral replication

Question 20

cells involved in innate immunity?

Answer 20

neutrophils
macrophages 
monocytes 
basophils 
eosinophils 
natural killer cells

Question 21

what cells have TLRs?

Answer 21

neutrophils and macrophages

Question 22

what does a ligand binding to a receptor do?

Answer 22

induces actin polymerisation causing phagocytes plasma membrane to surrond pathogen

Question 23

what proteins are involved in the inflammatory response?

Answer 23

acute phase proteins

Question 24

MBLs

Answer 24

binds to bacterial surface with particular arrangement

Question 25

CRPs

Answer 25

bind to phosphorylcholine on bacterial surface

Question 26

compliment

Answer 26

binds to bacterial surface

Question 27

what does the second line of defence include?

Answer 27

phagocytosis, chemotaxis and inflammation

Question 28

what is the compliment system?

Answer 28

30 proteins which compliment the action of the immune system, in the plasma

Question 29

what is the classical pathway?

Answer 29

an antibody binding to the pathogen

Question 30

what is the lectin pathway?

Answer 30

a mannose sugar on the pathogen surface binding leptin

Question 31

what is the alternative pathway?

Answer 31

spontaneous binding