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RMT 2025 > Immunology And Serology (HISTORY) > Flashcards

Immunology And Serology (HISTORY) Flashcards

1
Q

Who was able to demonstrate the 1st cross-immunity?

A

Edward Jenner

Edward Jenner’s work laid the foundation for immunology.

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2
Q

What disease does the variola major virus cause?

A

Smallpox

Variola major is a severe form of smallpox with high mortality rates.

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3
Q

What is the significance of the blood transfusion performed on Pope Innocent VIII?

A

It was one of the earliest recorded blood transfusions

This event highlights the historical attempts at blood transfusion before modern techniques were developed.

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4
Q

What did Braxton and Hicks recommend in 1869?

A

Sodium phosphate

This recommendation was related to medical treatments of that era.

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5
Q

What substance was introduced by Loutit and Molison in 1943?

A

ACD

Citrate is used as an anticoagulant in blood transfusions.

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6
Q

Who introduced the gel test in 1985?

A

Yves Lapierre

The gel test is used in serological testing.

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7
Q

What role did Dr. Charles Drew have in relation to blood banks?

A

Director of the American Red Cross blood bank

Dr. Drew was instrumental in developing blood storage and transfusion techniques.

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8
Q

What nickname was given to Mary Mallon due to her actions?

A

Typhoid Mary

She was a carrier of Salmonella typhi and unknowingly infected others.

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9
Q

Fill in the blank: Vaccinia causes _______.

A

Cowpox

Vaccinia is used in the smallpox vaccine.

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10
Q

What was introduced by Gibson in 1957?

A

CPD

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11
Q

Variolation:

A

Inhalation of pulverized small pox lesion crust.

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12
Q

Variola minor:

A

Alastrin

Mild small pox

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13
Q

In 1914, Hustin introduce _____.

A

Sodium Citrate

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14
Q

Marry Mallon:

A

Carrier of salmonella typhi

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15
Q

Who demonstrated that protection from smallpox could be generated by the transfer of pustular material from a cowpox lesion?

A

Edward Jenner

Edward Jenner’s work laid the foundation for vaccination.

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16
Q

What significant discovery did Louis Pasteur make?

A

Therapeutic vaccination

Pasteur’s work on vaccination was crucial in developing vaccines for various diseases.

17
Q

What was the first report of a live (attenuated) vaccine for rabies?

A

Modified organism

This marked a significant advancement in the field of immunology.

18
Q

Who demonstrated that cells could ingest foreign material, now classified as phagocytes?

A

Eue Merchnikov

This discovery was fundamental in understanding immune response.

19
Q

What did Jules Bordet discover?

A

Complement

Bordet’s discovery contributed to the understanding of immune system functions.

20
Q

Who discovered precipitins?

A

Robert Kauffman

This work was important for understanding antibody responses.

21
Q

Who won the Nobel Prize for his work on antitoxins?

A

Emil Adolf von Behring

His research was pivotal in the development of serum therapy.

22
Q

What discovery was awarded the Nobel Prize in 1978 regarding antibodies?

A

Genetic principles underlying the generation of antibodies with different specificities

This work was crucial for immunology and genetics.

23
Q

Who demonstrated the structure of antibodies?

A

Gerald Edelman and Rodney Porter

Their work advanced the understanding of immunoglobulin structure.

24
Q

What concept did Niels Jerne demonstrate?

A

Immunoregulation

Jerne’s work contributed to the understanding of how the immune system regulates itself.

25
Q

What was significant about the blood transfusion performed on Pope Innocent V?

A

It was one of the first recorded blood transfusions

This event highlights early medical practices in blood transfusion.

26
Q

Who were awarded the Nobel Prize for their work on HIV?

A

Françoise Barré-Sinoussi and Luc Montagnier

Their research was crucial in the understanding of the HIV virus.

27
Q

What disease does Variola major cause?

A

Smallpox

Variola minor is a less severe form of the disease.

28
Q

What practice did the Chinese use to combat smallpox?

A

Variolation

This ancient practice involved the inoculation with powdered smallpox lesions.

29
Q

What did Braxton and Hicks recommend in 1869?

A

Sodium phosphate

Their recommendations contributed to medical practices at the time.

30
Q

What did Dr. Charles Drew accomplish in 1941?

A

Appointed director of the Red Cross blood bank

Drew’s work was instrumental in blood donation and transfusion practices.

31
Q

What important medical advancement was introduced by Loutit and Molison in 1943?

A

Blood transfusion techniques

Their work improved the safety and efficiency of blood transfusions.

32
Q

Who was known as ‘Typhoid Mary’?

A

Mary Mallon

She was a carrier of Salmonella typhi and unknowingly infected others.

33
Q

What significant test was developed by Lapterl in 1985?

A

Gel test

This test contributed to advancements in diagnostic techniques.

RMT 2025 (1 decks)

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