Immunology

Question 1

Granulocytes

Answer 1

Neutrophils
Eosinophils
Basophils

Question 2

Agranulocytes

Answer 2

Monocytes

Lymphocytes

Question 3

Distribution of WBC

Answer 3

Never Let Monkeys Eat Bananas
Neutrophils 62%
Lymph
mono
eosi
baso

Question 4

Neutrophils

Answer 4

First responders

• best against bacteria
• adhere to vascular endothelium and squeeze through endothelium and phagocytosis to kill antigen

Question 5

Increase in Metamylocyte

Answer 5

AKA band neutrophils (>8%)

• leukocytosis “left shift”
• means bone marrow signaled to realsed more WBC
• signal of bacterial inf

Question 6

Neutrophilia vs. Neutropenia

Answer 6

philia: elevated
Penia: low count

Question 7

Basophils

Answer 7

role in allergic and antigen response
- release histamine
and heparin (reduce clotting)

Question 8

Eosinophils

Answer 8

Target larger parasites

• also modulates allergic inflammatory response
• rare in blood! more in mucous membranes (thats where we would encounter parasites)

Question 9

Mast Cells

Answer 9

Release Histamine

• BIG player in anaphylaxis
• present in barrier tissues

Question 10

Monocytes

Answer 10

Largest WBC
-found in blood and SPLEEN
- primary good for virus!!
differentiate into macrophages and dendritic cells

Question 11

What cells do Lymphocytes differentiate into

Answer 11

B cell, T cell and NK cells

Question 12

Primary Lymp Organs

Answer 12

B- cells mature in bone marrow
Thymus: t cells mature
* both made in bone marrow

Question 13

Bone Marrow

Answer 13

Primary-B cells mature

Question 14

Thymus

Answer 14

Primary: t cells mature

• behind sternum
• may show up as thymic sail sign on X-ray in little kids

Question 15

Spleen

Answer 15

removes onld RBC, holds storage of RBC, recycles ion

• synthesizes antibodies!!
• removes antigens as well

Question 16

what bacteria are asplenic patient more susceptable to

Answer 16

strep pneumonia
h. influenza
N. meningitis
* cannot get live vaccines

Question 17

Lymphnodes

Answer 17

filter foregin molecules and cancer cells

1mm to 1-2 cm

Question 18

Tonsils/adenoids

Answer 18

first line of defense for ingested or inhaled pathogens

-combat common respiratory illness

Question 19

MALT

Answer 19

• concentrations of lymphoid tissue
• populated by mature B and T cells
• specialized in antigens passing through epithelium