immunology Flashcards
primary immune response
occurs the first time an immune system encounters, generates memory cells with high specificity, can take 14 days
secondary immune response
occurs following a previous encounter, more rapid, previously generated
five types of immunoglobulins
IgG, IgA, IgM, IgD, IgE
IgE
hypersensitivity (allergies and parasite), present in serum in lowest concentration of all Igs
IgD
unknown function, found in B cells
IgM
First Ig produced in immune response, most efficient complement fixing Ig. Pentamer
IgA
Major Ig. Dimer
types of vaccines
live attenuated, inactivated, subunit, toxoid
live attenuated
similar to natural infection, stored in cool place, can cause disease in weakened immune system.
inactivated
uses killed version of pathogen, may need boosters, will not weaken immune
subunit
uses dead pathogen in pieces, strong specific response, may need booster, fine for weak people
toxoid vaccines
uses a toxin made by the pathogen, tetanus, my require boosters, safe for weak.
infants
cannot produce antibodies until 3-6 months
innate
inborn, present at all times, responds immediately, responds uniform
acquired
6 days to respond, antigen specific, keeps memory
types of white blood cells
neutrophils, eosinophil, basophil
neutropenia
decrease in neutrophils can cause a severe infection
neutrophilia
increase in neutrophils, bacterial infection, drug intox, tissue necrosis.
neutrophil function
move to site of pathogen engulf it and destroy it. Adherence, migration, phagocytosis, bacterial killing
lymphocytes
includes b cell t cell and natural killer cells
t lymph function
cell mediated immunity
b lymph function
part of the humoral immunity can bind to antigen
natural killer cells function
kill infected cells
eosinophils function
reddish orange granules allergic disease, parasite infections, and chronic inflammation.