Immunology Flashcards
Function of the lymphatic system
- Remove waste
- Facilitate immunity
- Transport lymph
Primary organs of the lymphatic system
Bone marrow
Thymus
Secondary organs of the lymphatic system
Lymph nodes
Spleen
Tonsils
Peyer´s patches
Structure of the bone marrow
Red - active
White - fat inactive
Immune function of the bone marrow
B-cell production and maturation
T-cell production NO maturation
Function of the thymus
Maturation of T-cells
Parts and main cell type found in the thymus
Cortex - B-cells
Paracortex T-cells
Medulla - Plasma cells, macrophages and lymphocytes
Parts and function of the spleen
Red pulp - RBC production
White pulp - WBC production
Knowing spleen function, what king of problem a patient will have in case of spleen dysfunction ?
- Immune deficiency due to less B-cells+less iGm and lack of complement and C3b
- Patients will be more susceptible to encapsulated bacterial infection due to need of complement + C3b to kill them
- RBC with changes due to abnormal destruction or clearance
What Clin path finding you will see in RBC with a spleen insufficiency ?
Howell-Jolly bodies
Target cells
Where does the peyer´s patches are found?
In the small intestine, between lamina propia and submucosa
What kind of cells in the small intestine are the immune cells that present antigens to B-cells?
M-cells