Immunologica Reaction Type B ADR

Question 1

Allergies- immediate onset

Answer 1

Type 1- IgE mediated Anaphylactic reaction

Question 2

Cross sensitivity of Penicillin and cephalosporin
Dextran (plasma expander)
X-ray contrast media

Answer 2

Type 1- IgE mediated Anaphylactic reaction

Question 3

Cytolysis- bread down of cells
Blood dyspraxia

Answer 3

Type 2- IgG and IgM cytotoxic reaction

Question 4

Chloramphenicol

Answer 4

Aplastic anemia (most severe)

Question 5

Methyldopa

Answer 5

Hemolytic anemia

Question 6

ASA/ Ibuprofen

Answer 6

Idiopathic thrombocytopenic purpurea (due to antibody attacks platelets)

Question 7

Serum sickness
Soluble antigen
Drug-induced Systemic lupus erythematosus (SLE)
Jarish-Herxheimer reaction

Answer 7

Type 3- IgG mediated Immune complex reaction

Question 8

Alamo known as die-off reaction
Due to the endotoxin produced by spirochetes due to antibiotic treatment such as Pen G

Answer 8

Jarish-Herxheimer reaction

Question 9

Occurs after days or weeks
Slow or delayed onset

Answer 9

Type 4- T-cell mediated delayed reaction

Question 10

Contact dermatitis by poison Ivy (urushiol)
Organ/tissue rejection
Mantoux test (tuberculin skin test

Answer 10

Type 4- T-cell mediated delayed reaction