Immunohistochemical Stains & Serum Markers Flashcards

1
Q

Keratin

IHC

A
  • Keratin = intermediate filament in epithelial cells
  • Keratin-pos = epithelial cell
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2
Q

S100

IHC

A

Defining stain for malignant melanoma

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3
Q

PAS

IHC

A
  • Used to detect mucus
  • PAS-pos = epithelial cell

Only epithelial cells secrete mucus

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4
Q

Desmin

IHC

A
  • Desmin = intermediate filament in muscle cells
  • Desmin-pos = muscle cell
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5
Q

CA-125

Serum marker

A

Used to monitor superficial epithelial carcinoma treatment & recurrence

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6
Q

Lactate dehydrogenase (LDH)

Serum marker

A

May be elevated with dysgerminoma

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7
Q

Alpha fetoprotein (AFP)

Serum marker

A

Often elevated with endodermal sinus tumor

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8
Q

Placental Alka

A
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