Immunohistochemical Stains & Serum Markers Flashcards
1
Q
Keratin
IHC
A
- Keratin = intermediate filament in epithelial cells
- Keratin-pos = epithelial cell
2
Q
S100
IHC
A
Defining stain for malignant melanoma
3
Q
PAS
IHC
A
- Used to detect mucus
- PAS-pos = epithelial cell
Only epithelial cells secrete mucus
4
Q
Desmin
IHC
A
- Desmin = intermediate filament in muscle cells
- Desmin-pos = muscle cell
5
Q
CA-125
Serum marker
A
Used to monitor superficial epithelial carcinoma treatment & recurrence
6
Q
Lactate dehydrogenase (LDH)
Serum marker
A
May be elevated with dysgerminoma
7
Q
Alpha fetoprotein (AFP)
Serum marker
A
Often elevated with endodermal sinus tumor
8
Q
Placental Alka
A