Immunohematology (Blood Bank) Flashcards

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1
Q

A branch of immunology that deals with the uses of immunologic principles to study and identify the different blood groups.

A

Immunohematology

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2
Q

An area in the clinical laboratory that collects blood products from donors and is responsible for preparation and storing whole blood and blood components for transfusion.

A

Blood Bank

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3
Q

In the hopes of curing him, he received blood by drinking blood from three young boys. Unfortunately, the pope and all three children died.

A

Pope Innocent VII (1492)

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4
Q

He performed the first animal-to-human transfusion by bloodletting a 16-year-old boy. He exchanged three ounces of boy’s blood to nine ounces of lamb’s blood.

A

Jean Baptist Denis (1667)

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5
Q

Who is the second patient of Jean Baptist Denis?

A

Anton Mauroy

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6
Q

He transfused sheep’s blood to a student.

A

Richard Lower

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7
Q

Performed the first human-to-human transfusion in 1795 but this was not documented.

A

Philip Syng Physick

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8
Q

Subsequently performed and published a set of animal experiments which proved that the donor and the recipient must be of the same species.

A

John Henry Leacock

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9
Q

In 1825, He successfully transfused a woman dying from postpartum hemorrhage with by transfusing blood from the woman’s husband.

A

James Blundell

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10
Q

Observed red cell lysis in the blood of a woman who died after receiving a transfusion of sheep blood. He also observed that incompatible transfusion reactions were associated with hemorrhage and congestion of the kidneys, lungs, and liver.

A

Emil Ponflick

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11
Q

Observed that human red cells would lyse when mixed with the sera of other animals. He set the stage for the study of the immunologic basis of blood incompatibility.

A

Leonard Landois

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12
Q

Recommended the use of an anticoagulant.

A

Braxton Hicks

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13
Q

Discovered the ABO blood group and explained the serious reactions that occur in humans as a result of incompatible transfusions in 1901.

A

Karl Landsteiner

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14
Q

The clumping of cells.

A

Agglutination

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15
Q

Discovered the fourth less frequent blood group “AB”.

A

Alfred von Descatello and Adriano Sturli

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16
Q

Discovered the Rh blood group.

A

Karl Landsteiner and Alex Weiner

17
Q

The units of heredity; Often defined at the molecular level as a DNA sequence and are responsible for expression of a trait.

A

Genes

18
Q

One of two or more alternate forms of a gene.

A

Allele

19
Q

The set of genes possessed by an individual organism.

A

Genotype

20
Q

A physical trait whose expression depends on the inherited genes along with environmental factors.

A

Phenotype

21
Q

The phenomenon of one variant of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome.

A

Dominant

22
Q

A trait resulting from an allele that is independently and equally expressed along with the other.

A

Codominant

23
Q

A trait that is expressed only when genotype is homozygous; a trait that tends to be masked by other inherited traits, yet persists in a population among heterozygous genotypes.

A

Recessive

24
Q

Testing the compatibility of the donor blood and the recipient blood.

A

Crossmatching

25
Q

This detects if the recipient has antibodies which can destroy the transfused red blood cells from the donor.

A

Major Crossmatch: RSDC (Recipient Serum + Donor Cells)

26
Q

This detects if there are antibodies in the donor’s serum that can destroy the patient’s red blood cells.

A

Minor Crossmatch: DSRC (Donor Serum + Recipient Cell)

27
Q

FOR BLOOD TYPING, KINDLY REFER TO THE MODULE FOR BETTER UNDERSTANDING. KAYA?

A

KAYANG KAYA!