Immunohematology Flashcards
AB showing enzyme affect +
Rh, P, Lewis, Kidd
Haptens
partial AGs, req carrier molecule to cause immune response
Reactions in transfusion fall into which immunity?
Humoral
Humoral Immunity?
B-cells, and the cells they create, Plasma cells and Memory B-cells
ABs read @ IS?
A, B, H, I, M, N, Lewis, P
ABs read @ 37 degrees?
Rh, S/s, Lutheran, Duffy, Kidd, Kell
Non- HTR related ABs?
M, N, Lewis, P
AB that reacts @ 37 & AHG?
Rh
AB that reacts @ IgG biphasic temp?
Auto Anti-P
Donath-Landsteiner test W/ a fresh specimen does what?
A (+) indicates PT complement binds @ lower temps and causes hemolysis @ higher temps.
Dextrose does what to stored blood?
ATP by glycolytic pathway
Adenine does what to stored blood?
Substrate for RBC ATP synth
Sodium Biphosphate does what to stored blood?
Prevents excessive pH decrease
Mannitol does what to stored blood?
Osmotic diuretic for membrane stabilization
Anti-Coag CPD storage limit?
21 days