Immunodeficiency Flashcards
1
Q
What are the primary lymphoid tissues?
A
Bone Marrow
Thymus
2
Q
What are the secondary lymphoid tissues?
A
Spleen
Lymph Nodes
Tonsils
Payer’s Patches
3
Q
What are the main consequences of immuno-deficiency?
A
Infection
Cancer
4
Q
What are the main consequences of hyperimmunity?
A
Auto-immune
Allergy
5
Q
What are the primary immunodeficiencies?
A
Inherited
Congenital
6
Q
What are secondary immunodeficiencies?
A
Acquired
7
Q
Give an example of a secondary immunodeficiency
A
HIV Steroid use Splenectomy Leukaemia/Lymphoma Malnutrition
8
Q
Give an example of a primary immunodeficiency
A
Severe Combined Immunodeficiency (inherited stem cell defect) DiGeorge Syndrome (defect of development of pharyngeal arches)
9
Q
What are the antibody isotypes?
A
IgM (Pentamers)
IgG (Monomers)
IgA
IgE (Monomers)