Immunodeficiencies

Question 1

Most common immunodeficiency

Answer 1

Selective IgA deficiency

Question 2

Most severe ID
✖️T cell
✖️B cell

Answer 2

SCID

Question 3

Children are enclosed in a plastic bubble “bubble boy”

Answer 3

SCID

Question 4

✖️B cells

✖️All Ig’s

Answer 4

Bruton’s agammaglobulinemia

Question 5

Other name for Bruton’s agammaglobulinemia

Answer 5

X-linked hypogammaglobulinemia

Question 6

Wiskott-Aldrich Sx TRIAD

Answer 6

TIE

Thrombocytopenia
ID
Eczema

Question 7

✔️Uncoordinated mse movements (?)
✔️Dilation of blood vessels (?)
✔️Decrease ⬇️ levels if IgA, IgG2, IgE (Ig:A.G.E)

Answer 7

Ataxia-Telangiectasia

Question 8

Recurrent Bacterial infxn and sinusitis

Selective igG def

Answer 8

Common Variable Immunodeficiency

Question 9

Marked ⬆️ IgM

⬇️ levels of other Ab’s

Answer 9

WALDENSTROM’S macroglobulinemia

Question 10

Defective adhesion protein (CD18) on surface of phagocytes

Answer 10

Leukocyte adhesion deficiency sx

Question 11

Absence of THYMUS GLAND (thymic aplasia) and T CELLS

Answer 11

DiGeorge sx