Immunocology

Question 1

Role of the immune system ?

Answer 1

-Protection from disease
-Waste disposal (lymphatic vascular system)
- Performs roles via immune responses
-Surveillance system

Question 2

Role of the lymphatic system?

Answer 2

Regulates immune response by transporting bacteria,foreign antigens and immune cells to lymph nodes and lymphoid organs

Question 3

Main cytokines in acute inflammation?

Answer 3

IL-1 IL-6 TNF-a

Question 4

What are the early stages of acute inflammation?

Answer 4

Phagocytosis
*Cell and protein activation
*Increased vascular permeability
*Recruitment of cells

Question 5

What are cytokines?

Answer 5

Proteins that regulate the intensity and duration of the immune response

Question 6

What are chemokines?

Answer 6

Cytokines that meditate chemotaxis

Question 7

What is an antigen?

Answer 7

Any substance that binds specifically to an antibody

Question 8

What is an epitope?

Answer 8

The portion of the antigen that is recognised by an antibody

Question 9

What are the functions of an antibody ? (5)

Answer 9

Neutralisation
Agglutination
Complement activation
Opsonisation
NK cell activation

Question 10

Role of CD4+ T cells?

Answer 10

Secrete cytokines that determine and regulate immune response

Question 11

Role of CD8+ T cells?

Answer 11

Kill abnormal self cells