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Immuno Matching > Immuno Matching Test 1 > Flashcards

Immuno Matching Test 1 Flashcards

1
Q

Enhances bacterial uptake by neutrophils via opsonization

A

C3b

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2
Q

Iron chelating protein present in neutrophils

A

Lactoferrin

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3
Q

Expresses CD3 signal transducer

A

T-Cell

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4
Q

Source of the inflammatory mediator histamine

A

mast cells

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5
Q

Granulocytic cell that has specialized role in immunity to parasites

A

Eosinophiles

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6
Q

Interdigitating dendritic cells

A

Langerhans cells

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7
Q

Accounts for the secondary effector functions of an antibody molecule

A

Fc portion

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8
Q

Ability of a cytokine to affect multiple cell types

A

Pleiotropism

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9
Q

Bacterial component susceptible to lysozyme degradation

A

Peptidoglycan

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10
Q

Accounts for the pain observed in acute inflammatory reactions

A

bradykinin

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11
Q

MHC protein present on some cell membranes

A

MHC class II

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12
Q

Chemical mediator of inflammation produced by mast cells

A

histamine

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13
Q

Membrane attack complex of the complement system

A

C5b6789

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14
Q

Mature lymphocytes can be demonstrated in the medullary area

A

Thymus

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15
Q

Helps convert H2O2 into H20 and O2

A

Gluthathione peroxidase

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16
Q

facilitates binding of complement- coated bacterial cells to neutrophils

A

CD35

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17
Q

Possesses primary and secondary granules

A

Neutrophil

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18
Q

Location of B cells in the spleen

A

White pulp

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19
Q

Source of thymic hormones

A

Thymic epithelial cells

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20
Q

Synonym for humoral immunity

A

B-cell immunity

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21
Q

Selectin protein on neutrophil that mediates rolling

A

L-selectin

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22
Q

Product of respiratory burst tht degrades bacterial DNA

A

H2O2

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23
Q

Presents endogenously derived epitopes to T- cells

A

MHC class I

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24
Q

Mucosa associated lymphoid tissue

A

Peyers patches

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25
Q

product of respiratory burst resulting in oxidation of bacterial lipids

A

Hydroxyl radical

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26
Q

Presents processed epitopes to helper T cells

A

MHC class II

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27
Q

Complement enzyme stabilized by properdin

A

C3bBb

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28
Q

Natural Killer cell receptor that binds IgG

A

CD16

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29
Q

Complement pathway triggered by antigen- antibody complexes

A

Classic Complement pathway

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30
Q

Also known as antigenic determinant

A

Epitope

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31
Q

Chemotactic agent derived from bacterial cells

A

N-formyl peptides

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32
Q

Adhesion molecule on T- cell that binds to counter receptor on APS

A

CD2

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33
Q

A terminally-differentiated antibody secreting cell

A

Plasma cell

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34
Q

Endothelial cell derived cytokine increasing affinity of neutrophil integrins and is also chemotactic for the neutrophil

A

Interleukin 8 ( CXCL8)

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35
Q

Proteins that participate in the activation of the classical complement pathway

A

C2/C4 proteins

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36
Q

MHC protein that presents proteasome derived peptides to T- cells

A

MHC class-1

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37
Q

Bone marrow derived blood cell that is the precursor of tissue macrophages

A

Monocyte

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38
Q

Source of pre-B and pre-T lymphocyte stem cells

A

Bone marrow

39
Q

Mononuclear phagocytes that provide continuing defense against infections of the brain

A

Microglial cells

40
Q

Mature T and B lymphocyte can be demonstrated in the PALS

A

Spleen

41
Q

Induces immune response classified as active natural immunity

A

Infection

42
Q

Primary phagocytic cells

A

Neutrophils

43
Q

Cell membrane protein that inhibits assembling of the membrane attack complex of the complement cascade, preventing “bystander lysis”

A

CD59

44
Q

Provides an environment for lymphocyte interaction with antigen

A

Spleen

45
Q

Chemotaxin that facilitates leukocyte accumulation

A

C5a

46
Q

A marker for helper T cells

A

CD4

47
Q

APC’s responsible for long-term retention of antigens in some peripheral lymphoid organs

A

Follicular dendritic cells

48
Q

Alternative complement pathway protein that cleaves factor B bound to C3b

A

Factor D

49
Q

1st line of defense in CT against bacterial invasion

A

hisiocytes

50
Q

An activator of the alternative complement pathway

A

Lipopolysaccharide

51
Q

Cd4689T5b protein

A

HAHAHAHAHA just fucking with you I made those up….. keepin ya on your toes!
( ya just freaked a little didn’t ya)

52
Q

MHC protein consisting of alpha and beta protein chains

A

MHC class-2

53
Q

Iron binding protein produced by hepatocytes that impairs replication of bacteria

A

haptoglobin

54
Q

Receptor facilitating binding of IgG to NK cells in antibody-dependent cell mediated cytotoxicity

A

CD16

55
Q

Regulatory protein that inactivates unwanted C3b to giving rise to iC2b

A

Factor 1

56
Q

Vasoactive mediator of inflammation derived from plasma protein

A

Bradykinin

57
Q

Expression of CD2 and CD8 markers

A

Cytotoxic T-cell

58
Q

A measure of the binding strength between antibody and antigen

A

Affinity

59
Q

Cytotoxic T-cell derived proteins inserting themselves into target cell membrane inducing lysis

A

perforin

60
Q

Immunoglobulin superfamily protein mediating leukoctyte adhesion

A

ICAM-1,2,3 VCAM-1

61
Q

Also known as the memory response

A

Secondary immune response

62
Q

Site of maturation of NK cells

A

Bone marrow

63
Q

Coded for by the HLA-A gene

A

MHC Class-1

64
Q

A ligand recognized by CD35 on phagocytic cells

A

C3b

65
Q

Example of a peripheral lymphoid organ

A

BONE MARROW

66
Q

Cytolytic enzymes found in the granules of cytotoxic T- cells and NK cells

A

Granzymes

67
Q

Site on the antibody that recognized epitopes on the antigen

A

Complementarity-determining region

68
Q

Plasma protein made up mostly of antibodies

A

Gamma Globulin

69
Q

Helper T-cell costimulatory molecule found on B cell membranes

A

B7-2

70
Q

Function as both professional phagocytes and APC’s

A

Macrophages

71
Q

Adhesion molecule on vascular endothelial cell facilitating extravasation

A

VCAM-1

72
Q

Inactivates complement protein C3b

A

Factor 1

73
Q

Found in the cortex lymph nodes

A

B-cells

74
Q

Also known as immune response genes

A

MHC class -2

75
Q

Cross reacting antigen

A

Heterologous antigen

76
Q

phagocytic in the liver

A

Kupffer cells

77
Q

Granulocytic cell

A

Neutrophil

78
Q

Site of immune response

A

lymph node

79
Q

A chemotaxin derived from membrane phospholipid

A

LTB4

80
Q

Increase in numbers may result in autoimmune disease

A

Helper t- cells

81
Q

Associated with activation of macrophaged

A

Lipopolysaccharide

82
Q

Eosinophil enzyme involved in parasite killing

A

Eosiniphil cationic protein

83
Q

Complement proeins cleaved by C1’s

A

C2 and C4 proteins

84
Q

Bacterial cell capable of growth in a macrophage

A

Mycobacterium bovis

85
Q

Stabilizes the complement enzyme C3bBb

A

Properdin

86
Q

T-independent antigen

A

polysaccharide

87
Q

Recognition site on C1 protein

A

C1q

88
Q

Mammalian equivalent of the avian bursa of fabricius

A

bone marrow

89
Q

Synonym for primary lymphoid organs

A

Central lymphoid organs

90
Q

Progenitor cells of giant cells

A

Macrophage

91
Q

Recognition of MHC 1 molecule on APC’s

A

CD8

92
Q

Located in germinal centers of lymph nodes

A

B-cells

93
Q

An alpha chemokine

A

Interleukin -8

94
Q

Tc Cell product resulting in lysis of target cell

A

Lymphotoxin

Immuno Matching (1 decks)

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