Immuno-hémato Flashcards

1
Q
A

Leflunomide

Antimétabolite ; inh réversible de la dihydroorotate déshydrogénase

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2
Q
A

Teriflunomide

Antimétabolite ; inh réversible de la dihydroorotate déshydrogénase

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3
Q
A

Dimethyl fumarate

Blocage de NFkB

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4
Q
A

Cladribine

Inh de la ribonuycléotide-réductase et ADN polymérase alpha

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5
Q
A

Mycophénolate mofétil

Antimétabo ; Inh révers non compétitif de impdh (synth bases puriques)

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6
Q
A

Fingolimod

Modulateur des récepteurs S1P

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7
Q
A

Ciclosporine

Inh de prod des cytokins ; inh de l activité phosphatase de calcineurine

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8
Q
A

Sulfasalazine

Anti-inflammatoire intestinal

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9
Q
A

Prednisolone

Corticoïde

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10
Q
A

Prednisone

Corticoïde

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11
Q
A

Biotine

Immunosuppresseur ; sous ATU

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12
Q
A

Hydroxychloroquine

Anti-inflammatoire

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13
Q
A

Tacrolimus

Inh de prod des cytokins ; inh de l activité phosphatase de calcineurine

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14
Q
A

Mitoxantrone

Agent intercalant ; inh de la topoisomérase ; IV

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15
Q
A

Sirolimus

Inh de production des cytokines ; inh de l activité de la kinase mTOR

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16
Q
A

Everolimus

Inh de production des cytokines ; inh de l activité de la kinase mTOR

17
Q
A

Guanylhistamine

18
Q
A

Histamine

19
Q
A

Méthotrexate

Antimétabolite ; Inh de la dihydrofolate réductase

20
Q
A

Cyclophosphamide

Agent alkylant ; prodrogue

21
Q
A

Azathioprine

Inh synthèse des bases puriques ; dérivé imidazolé de 6-mercaptopurine

22
Q
A

6-mercaptopurine

Antimétabolite ; inh compétitif synthèse des bases puriques