immuno drugs Flashcards

1
Q

histamine

A

smooth muscle constriction, increased vascular permeability

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2
Q

Eosinophils ECF-a

A

chemotactic cytokines neutral proteases, and hydrolases

Initiate type 1 hypersensitivity response

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3
Q

anti-histamine

A

compete with histamine at receptor

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4
Q

chromolyn sodium

A

Stabilizes mast cell membrane

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5
Q

Corticosteroid

A

Prevent arachadonic acid pathways

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6
Q

EPi

A

Reverses histamine

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7
Q

Omalizumab

A

Anti-IgE antibody

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8
Q

Monteleukast

A

Leukotriene D4 blocker

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9
Q

corticosteroid allograft rejection

A

Inhibit lymphocyte gene expression

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10
Q

Anti metabolites

A

Purine antagonist, DNA alkylating agents

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11
Q

Blocking agents

A

administer CD3 MAb blocking Tcell activation against IL-2R

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12
Q

cyclosporine, FK 506, Irradication

A

interferes with T cell transcription, to include IL-2 IL-4, IFN-g, IL-2R

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