immuno drugs Flashcards
histamine
smooth muscle constriction, increased vascular permeability
Eosinophils ECF-a
chemotactic cytokines neutral proteases, and hydrolases
Initiate type 1 hypersensitivity response
anti-histamine
compete with histamine at receptor
chromolyn sodium
Stabilizes mast cell membrane
Corticosteroid
Prevent arachadonic acid pathways
EPi
Reverses histamine
Omalizumab
Anti-IgE antibody
Monteleukast
Leukotriene D4 blocker
corticosteroid allograft rejection
Inhibit lymphocyte gene expression
Anti metabolites
Purine antagonist, DNA alkylating agents
Blocking agents
administer CD3 MAb blocking Tcell activation against IL-2R
cyclosporine, FK 506, Irradication
interferes with T cell transcription, to include IL-2 IL-4, IFN-g, IL-2R