Immuno - Antibodies Flashcards

1
Q

Antiphospholipid Syndrome (APS)

A

anti-cardiolipin, lupus anticoagulant

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2
Q

AI hepatitis

A

Anti-smooth muscle antibody

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3
Q

Churg-Strauss/eGPA

A

p-ANCA

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4
Q

Coeliac

A

anti-Tissue Transglutaminase Antibody (TTG), Anti-Endomysial Antibody (AMA)

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5
Q

Dermatitis herpetiformis antibody and association

A

anti-endomysial (think coeliac associated)

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6
Q

Dermatomyositis

A

Anti-Jo1

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7
Q

Diffuse scleroderma

A

Anti-scl70 (topoisomerase)

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8
Q

Limited scleroderma (CREST)

A

Anti-centromere

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9
Q

Goodpasteur’s

A

anti-GBM

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10
Q

Graves

A

anti-TSHr (stimulatory)

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11
Q

Hashimoto’s

A

anti-thyroglobulin and anti-thyroid peroxidase

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12
Q

Microscopic polyangitis (MPA)

A

p-ANCA

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13
Q

Myasthenia Gravis

A

Anti-ACh receptor

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14
Q

Pernicious anaemia

A

anti-parietal cell and anti-intrinsic factor

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15
Q

Polymyositis

A

Anti-Jo1

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16
Q

PBC

A

Anti-mitochondrial antibodies

17
Q

RA

A

Anti-Cyclic Citrullinated Peptide (most specific), Rf

18
Q

SLE antibodies

A

Anti-dsDNA (most specific)

Anti-Ro, La, Sm (anti-ENAs)

19
Q

Sjögrens

A

Anti-Ro, Anti-La (anti-ENAs)

20
Q

T1DM

A

Anti-Glutamate Decarboxylase and Pancreatic ß cells

21
Q

What is the most specific marker for Rheumatoid arthritis:

a. Anti-nuclear antibodies
b. Anti-cyclic citrullinated protein
c. Rheumatoid factor
d. Tissue-transglutaminase antibody
e. Anti-dsDNA antibodies

A

b. Anti-cyclic citrullinated protein