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Gastrointestinal > Immuno > Flashcards

Immuno Flashcards

1
Q

Serum autoantibodies against what enzyme are specifically associated with celiac disease?

A

Tissue transglutaminase (TG2)

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2
Q

Celiac disease has a strong association with what other type of disorder?

A

Autoimmune

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3
Q

Gluten is hard to digest because it is proline rich and we lack what?

A

Prolyl endopeptidases

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4
Q

Celiac disease is what type of hypersensitivity?

A

Type 4 because it is cell/antigen mediated

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5
Q

What molecules are the main genetic predisposing factors for celiac disease?

A

HLA-DQ2 and DQ8

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Gastrointestinal (9 decks)

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