Immuno Flashcards
1
Q
Hypersensitivity reactions
“ABCD”
A
Anaphylactic/Atopic Type 1
anti-Body-mediated Type 2
immune Complex Type 3
Delayed CMI Type 4
2
Q
Type 1 Hypersensitivity
A
Immediate (minutes) -
- antigen crosslinks of preformed IgE on mast cells (immediate degranulation & histamine release)
Late (Hours)
- chemokines attract eosinophiles to mast cells causing inflammation & tissue damage