Immuno Flashcards

1
Q

Hypersensitivity reactions
“ABCD”

A

Anaphylactic/Atopic Type 1

anti-Body-mediated Type 2

immune Complex Type 3

Delayed CMI Type 4

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2
Q

Type 1 Hypersensitivity

A

Immediate (minutes) -
- antigen crosslinks of preformed IgE on mast cells (immediate degranulation & histamine release)

Late (Hours)
- chemokines attract eosinophiles to mast cells causing inflammation & tissue damage

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