Immuno Flashcards
1
Q
Main effect of the three cytokines released during cytokine storm
A
IL-1 - fever
IL-6 - regulates acute phase proteins
TNF-a - Shock
2
Q
Classic complement pathway activation
A
C-reactive protein binds microbial surface molecules
3
Q
Alternate complement pathway activation
A
spontaneous hydrolization of C3
4
Q
Lectin complement pathway activation
A
MBL protein
5
Q
MAC
A
MEmbrane attack complex in complement. lysis bacterial cells.
6
Q
C3b function
A
opsonization for phagocytosis
7
Q
C3a and C3b function
A
activates mast cells and mediates chemotaxis of blood cells into damaged tissue
8
Q
Gram + recognized by what receptor
A
TLR2 and 6
9
Q
Gram - recognized by what receptor
A
TLR4
