immunization quiz 2 Flashcards

1
Q

identify patients that are at risk for covid

A
  • age: >65 years and very young children
  • conditions: obesity, diabetes, kidney disease, COPD, neurocognitive disorders, heart conditions
  • conditions are additive for risk
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2
Q

explain risks of covid

A
  • complications include pneumonia, myocarditis, blood clots, neurologic effects, long-COVID
  • reinfection can happen
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3
Q

identify and explain when based on CDC recommendations patients should receive COVID vaccine

A
  • primary series of 2 (or 1 Janssen) recommended. mixing not authorized for primary doses
  • Janssen boosters: 1 bivalent booster
  • age 12+ booster: 1 bivalent booster
  • age 5-11: Pfizer booster (monovalent)
  • age 6mo-4yrs: primary series only
  • immunocompromised people get an extra dose of primary series (considered separate than booster)
  • if patient has received monoclonal antibodies, wait 2 weeks after vaccination and continue with additional doses
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4
Q

identify vaccine specific adverse effects to covid

A
  • injection site pain
  • fatigue
  • headache
  • myalgia
  • adverse effects tend to be mild to moderate, happening 1-2 days from vaccine
  • can be more frequent and severe after 2nd dose
  • kids: injection site pain, fatigue, irritability, drowsiness, febrile seizures possible, also tend to be mild to moderate overall
  • myocarditis (but there’s a higher risk with infection than vaccine, most common in males 12-39, increasing intervals between doses may help)
  • Janssen also has risk of thrombosis, only recommended if it’s the only option, tell patients to look out for symptoms up to 2 weeks after (shortness of breath, chest pain, leg swelling, persistent abdominal pain, headache, easy bruising)
  • very rare anaphylactic reaction
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5
Q

explain dosage, storage, administration technique, and schedule for covid vaccine

A
  • Pfizer age 6mo-4years: 0.2mL
  • Pfizer age 5-11: 0.2mL primary series, 0.2mL booster
  • Pfizer 12+: 0.3mL primary series, 0.3mL booster
  • Moderna 6mo-5years: 0.25mL
  • Moderna 6-11: 0.5mL
  • Moderna 12-17: 0.5mL
  • Moderna 18+: 0.5mL primary series, 0.25mL booster dose
  • Janssen 18+: 0.5mL
  • Novavax 12+: 0.5mL
  • storage depends per vaccine but generally fridge or freezer?, usually ok 12 hrs from opening but varies per vaccine
  • all IM
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6
Q

identify contraindications for covid vaccine

A
  • history of severe allergic reaction to previous dose/ to a component of COVID vaccine
  • diagnosed allergy to component of COVID vaccine
  • Janssen: TTS following previous Janssen COVID vaccine
  • Janssen: not recommended if history of immune syndrome related to thrombosis
  • Janssen: not recommended if Guillain Barre Syndrome occurs within 6 weeks of previous dose
  • Janssen: precaution with any history of GBS
  • precaution if history of an immediate allergic reaction to any vaccine other than COVID
  • precaution if a non-severe, immediate allergic reaction to a previous dose occurred
  • precaution if moderately to severely ill
  • precaution if history of MIS-C or MIS-A
  • precaution if history of myocarditis or pericarditis after a dose of a COVID vaccine
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7
Q

identify patients that are at risk for HIB related disease

A
  • crowded/ large household
  • daycare
  • school-aged siblings
  • chronic disease (sickle cell, cancer, etc)
  • low parental education
  • low socioeconomic status
  • males have slightly higher risk
  • race/ethnicity: African-Americans, Hispanics, Native Americans
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8
Q

explain what is severe/invasive HIB disease

A

related diseases include:]
- meningitis
- epiglottitis
- pneumonia
- arthritis
- osteomyelitis and bacteremia
- 6% mortality rate

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9
Q

identify and explain when based on ACIP/CDC recommendations patients should receive HIB vaccine

A

-primary series of 2-3 doses at 2, 4, and 6 months with a booster at 12-15 months

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10
Q

identify HIB vaccine adverse effects

A
  • local swelling, pain, redness
  • systemic fever, fussiness
  • severe reaction rare
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11
Q

explain dosage, storage, administration technique, and schedule for HIB vaccination

A
  • 0.5mL administered IM
  • stored in fridge
  • catch up recommended up to 5 years old
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12
Q

identify valid contraindications for HIB vaccine

A
  • no less than 6 weeks old
  • evaluate combination vaccine components
  • defer if moderate to severe illness
  • do not give if there is a known allergy to the vaccine or its components
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13
Q

identify patients at risk for meningococcal disease

A
  • most common in adolescents and young adults
  • highest risk groups: <1 and 19-22, college students during outbreak, microbiologists, asplenia increases fatality chance, complement inhibitor, persistent complement deficiency
  • host factors: deficiencies in terminal complement, asplenia, chronic underlying illness, genetic, HIV infected
  • exposure factors: household exposure, recent viral infection, household crowding, exposure to cigarette smoke, microbiologists
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14
Q

explain serious health effects from becoming sick with meningococcal disease

A
  • very rapid onset
  • 10-20% mortality
  • common complications when body goes into DIC: loss of limb, scarring, cerebral infarction
  • common complications with meningitis in 50% of cases: hearing loss and neurologic damage
  • meningococcemia in 40% of cases: high fever, rash, shock (hypotension and multiorgan failure), acute adrenal hemorrhage, death within hours of onset
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15
Q

identify and explain why patients require meningococcal vaccines based on CDC guidelines

A
  • Bexsero (men b): approved for 10-25years
  • Trumenba (men b): approved for 10-25 years
  • recommended for everyone?
  • at risk patients stay up to date on boosters, 1 vaccine lasts 3-5 years
  • Menactra (A,C,W,Y): approved for 9mo-55years
  • Meveo (A,C,W,Y): approved for 2mo-55years
  • Menquadfi (A,C,W,Y): approved for 2+ years
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16
Q

explain storage, administration technique, and schedules for meningococcal vaccination

A
  • dose 0.5mL IM
  • store in refrigerator
  • note that Menveo has a special reconstitution fluid
  • patients at high risk for men b should get revaccinated 1 year after first dose and continue to get it every 2-3 years if still at risk
17
Q

identify adverse effects of meningococcal vaccines

A
  • Bexero: injection site irritation, myalgia, fatigue, headache, nausea, arthralgia
  • Trumenba: injection site irritation, headache, myalgia, chills
18
Q

identify valid contradictions to meningococcal vaccination

A
  • severe allergic reaction
  • delay if moderate to severe illness
  • pregnancy NOT contraindication
19
Q

explain serious health effects and costs of becoming sick with pneumococcal disease

A
  • invasive bacteria can cause meningitis, bacteremia with or without pneumonia, osteomyelitis, peritonitis
  • non-invasive bacteria can still cause: pneumonia without bacteremia, otitis media, sinusitis
20
Q

identify and explain why patients are recommended to receive pneumococcal vaccines

A
  • high risk are young and old (especially old)
  • asplenia (and sickle cell)
  • immunodeficiency
  • chronic renal failure
  • cochlear implant
  • lung and WBC disease
  • seizure disorder, chronic liver disease, immunosuppressive drug/condition
  • chronic heart disease, neuromuscular
  • asthma, alcoholism, smoking, immunologic condition
  • diabetes, chronic oral steroids
  • pediatric recs: all infants need PCV13 or 15 3 dose series with booster at 12 mo. if high risk, get PCV23 if >2years
  • adult recs: routine for patients 65+, routine for high risk aged 19-64
  • if no record of PCV13: get PCV15 followed by PPSV23 1 year later or PCV20
  • if they have PCV13, they can have PPSV23
  • if they have PPSV23, they can get PCV15 or 20 1 year later
21
Q

explain pneumococcal vaccine efficacy and adverse effects

A
  • PPSV23- 21-46% effective against pneumonia, 38% against IPD; may cause injection site reaction, headache, fatigue, myalgia
  • PCV13- 75% effective against IPD, works better in children; may cause injection site reaction, irritability, decreased appetite, change in sleep pattern, fever, headache, muscle ache
  • PCV15- inferred from immunogenicity; may cause injection site reaction, fatigue, myalgia
  • PCV20- inferred from immunogenicity; may cause injection site reaction, fatigue, myalgias
22
Q

list dose, storage, administration technique, and schedule for pneumococcal vaccination

A
  • 0.5mL IM (but PPSV23 can also be done SQ)
  • all stored in fridge
  • suspensions must be shaken before being drawn up
23
Q

identify valid contraindications to pneumococcal vaccination

A
  • prior severe allergic reaction to pneumococcal vaccine
  • or prior severe allergic reaction to diptheria toxoid
  • delay if moderate to severe illness