IMMUNITY Flashcards
1ST LINE OF DEFENSE
1ST LINE - SKIN/ MUCOUS
PREVENT WIDE VARIETY OF MICROORGANISMS FROM ENTERING THE BODY/ INNATE
2ND LINE OF DEFENSE
2ND LINE- MICROORGANISMS PENETRATE THE BODY, PHAGOCYTOSIS, ANTIMICROBAL SUBSTANCES, FEVER, INFLAMMATION/ INNATE
3RD LINE OF DEFENSE
ELIMINATE SPECIFIC MICROORGANISMS THAT PENETRATE THE BODY/ PREVENTING IT FROM COMING BACK FOR FUTURE ATTACKS/ ADAPTIVE (SPECIFIC)
FOUR FUNCTIONS OF INFLAMMATION
REMOVES CELLULAR DEBRIS
REMOVES MICROBES
PREVENTS MICROBES FROM SPREADING
REPAIRS DAMAGED TISSUE
THREE STAGES OF INFLAMMATION
- VASODILATION, INCREASED PERMABILITY OF BLOOD VESSELS
- PHAGOCYTOSIS, PHAGOCYTE MIGRATION
ENGULFED AND KILLED BY LYSOMES - INFLAMMATION - TISSUE REPAIR
FOUR CHARACTERISTICS OF INFLAMMATION
PAIN, SWELLING, REDNESS, HEAT, LOSS OF MOVEMENT.
FUNCTIONS OF SPLEEN
FILTERING BLOOD
MAKING IMMUNE SYSTEM COMPONENTS
STORING BLOOD CELLS
PREVENTING INFECTIONS
SYNTHESISING HEMAGLOBINS
BENEFITS OF FEVER
RAISES TEMPERATURES SLOWS BACTERIA GROWTH
TEMPERATURE RAISE
DEFENSE MECHANISMS BECOME FASTER
INCREASE RATES OF CHEMICAL REACTIONS
MAKES PEOPLE FEEL ILL SO THE BODY RESTS AND GIVES THE BODY ENERGY TO FIGHT INFECTIon
FOUR CLASSES OF ANTIBODIES
IgG, IgA, IgM, Ige
igG
80% of the antibodies in serum
Protect against bacteria, neutralise toxins and viruses, trigger complement, make phagocytosis
cross the placenta so the foetus and new-born get some protection from mother
long lasting
igA
10-15% of antibodies in blood
most common antibody in secretions & on mucous membranes: found in
Mucus
Saliva
Tears
BREASTMILK
Binding antigens before the invade tissues
IgM
5-10% of antibodies
First type be produced when antigen
very good at clumping antigen and triggering component
IgE
Tiny amounts only
involved in allergic reactions
Play a role in immunity to parastic infections in guts
Functions of antibodies
- Enhance pathocytosis
- Activates components
- Neutralisation - to stop it binding to the host
- Agglutian
FOUR TYPES OF ACQUIRED IMMUNITY
NATURAL
ACTIVE - ENCOURAGING ANTIGEN
PASSIVE - ANTIBODY TRANSFER BY NATURAL MEANS
ARTIFICIAL
ACTIVE - VACCINATION
PASSIVE - ANTIBODY TRANSFER BY ARTIFICAL MEANS