Immunity Flashcards
Innate is
Non specific
Immunity present by birth
Innate
Name the 2 physical barrier
Skin and mucosa
Name the physiological barriers
Fever, ph and secretion
Secretion contains
Lyzozyme
Lyzozyme mostly kill
Bacteria
Name the bacteria present in vagina
Doderlein bacillus
Cellular Non phagocytic barrier
N-K cells
Phagocytic cellular barrier
Monocyte, macrophage and Neutrophil (PMNL)
Macrophage are modifications of
Monocyte
Macrophage are present in
Interstitial space
Foreign cell, transplant cell, tumour cell and virus infected cell are attacked by
N-K cells
N-K cell release_ and _ to attack
Perforin and Granzyme
Interferon are
Protein
Interferon is _ type of barrier
Cytokine
Interferon are secreted by
Virus infected cell
Interferon attack on
Healthy cell
Interferon never kill they
Inhibit further growth of virus
Protein formed on healthy cell after attacked by interferon
Translation inhibiting Protein
Prophylaxis
Action taken to prevent disease.
Inflammation occur on
Local tissue damage area
Write in correct order pain, heat, redness and swelling
Redness, heat, swelling, pain
Hormone released in inflammation
Histamine and Prostaglandin
CD present on T4 cell
CD4
CD 4 is present on
TH cell and macrophage
CD8 present on
TK cell
Acquired immunity is
Specific
Memory is present in which immunity
Acquired
Secondary response also called
Animalistic response
Im are formed after
Primary response
Memory cell are stored in
Secondary lymphoid organ
Memory cells
Tm and Bm
Antibody produced by
B lymphocyte
Doesn’t produce antibody but help in production
T lymphocyte
Antibody are _ chain
4
Antibody representation
H2L2
Chain are joined by
Disulphide bond
Epitope present in
Antigen
Antibody have
Paratope
Antibody and antigen reaction leading to cell lysis
Agglutination
Opunisation antibody
IgG and IgM
Neutralization
Neutralizing toxin of antigen
CMI
T lymphocyte
HMI
B lymphocyte
APCs have
MHC 2
APCs activate
TH cell
TH release
Lymphokines
B cell after activation by TH form
Antibody
TK cell after TH cell activation
Secrete perforin and lymphokines for cell lysis
Effector cell
TK cell
Antibody that release inhibitory chemical to supress immunity
TS cell
Immunity that has memory of antigen
Active immunity
Immunity for prevention
Active
Immunity for treatment
Passive
Which immunity work for immunodeficient host
Passive
Types of B lymphocyte
Bm and B plasma
Ig transferred form mother to foetus
IgG
Ig transferred from mother to infant
IgA
Main lymphoid organ
Bone marrow
Primary lymphoid organ
Bone marrow and thymus
In primary lymphoid organ immature lymphocyte convert into
Antigen sensitive lymphocyte
Primary lymphoid organ is place for
Orgin and multiplication
Secondary lymphoid organ
Spleen, tonsil, peyer patches, lymph node, apendix, MALT
In Secondary lymphoid organ
Storage ands Porifleration occur
First encounter of antibody and antigen occur in
Secondary lymphoid organ
Blood cells and lymphocyte are produced in
Bone marrow
Thymus location
Near heart beneath breastbone
Organ that provide micro-enviroment for development and maturation of T lymphocyte
Bone marrow and thymus
Phogocyte and lymphocyte are present in
Spleen
Spleen is large reservoir of
Erythrocyte
Organ acting as filter to blood born micro-organism
Spleen
50% of lymphoid tissue of body consist of
MALT
Hormone released by thymus during maturation of T lymphocyte
Thymosin
Presence of IgM in newborn
Indication of infection in Intra uterine life
Ig against Rh antogen
IgG
Ig against And B antigen of blood group
IgM
Better protection against pathogen is provided by
Acquired immunity
Universal and most abundant Ig
IgG
Ig that pass through placenta
IgG
Ig protecting body surface and is Secretory in nature
IgA
Ig that is oldest, strongest, largest, heaviest and has pentamer structure
IgM
IgM is max present in
Blood
Ig that’s present on surface and is fixed and stimulate B-lymphocyte for antibody production
IgD
Ig that is allergic
IgE
