Immune System Cells Flashcards
types of phagocytes
neutrophils, macrophages, dendritic cells, monocytes, mast cells
B lymphocytes
secrete specific antibodies after antigen recognition
TH1
recognises extracellular bacteria, increases macrophage killing, useful in secondary immune response
TH2
recognises worms and parasites, useful in primary immune response, if a child isn’t exposed to enough pathogens at a young age, their TH2 cell count will be too high in relation to TH1 cell count, and they will be at an increased risk of allergies, asthma, etc.
cytotoxic T lymphocytes
attack other cells; particularly useful against viruses; CD8+ T cells
natural killer cells
contain granules; attack cancerous/infected cells
types of granulocytes
basophils, eosinophils, neutrophils
basophils
prominent cytoplasmic granules; involved in allergic reactions; useful against parasties
eosinophils
contain a bilobed nucleus and granules; involved in allergic reactions/asthma; useful against parasites
mast cells
useful against parasites; mediate allergic reactions; release inflammatory chemicals e.g. histamine
monocytes
horseshoe-shaped nucleus; precursors of macrophages
neutrophils
granulocytes; prominent, multi-lobed nucleus; phagocytes; accumulate at site of injury, causing inflammation
dendritic cells
precursors of monocytes; presents antigens to B and T cells; expresses MHC I and MHC II
CD4+ T cells
any kind of helper T cell
IFNγ
activates macrophages in a positive feedback loop