Immune system

Question 1

what is the immune system “mantra”?

Answer 1

kill the pathogen, don’t harm the host

Question 2

is the innate immune system specific or non-specific?

Answer 2

non-specific

Question 3

is the adaptive immune system specific or non-specific?

Answer 3

specific “cognant antigen”

Question 4

monocytes give rise to…

Answer 4

macrophages and dendritic cells

Question 5

inflammation is an ________ immune cell response

Answer 5

innate

Question 6

Which cells act as a liaison between innate and adaptive immune systems?

Answer 6

dendritic cells

Question 7

what functions allow B cells to act like antibodies?

Answer 7

neutralization, opsonization and compliment activation

Question 8

all 3 functions of B cells lead to…

Answer 8

ingestion by a phagocyte

Question 9

What are the 3 specific types of T cells?

Answer 9

T helper, T killer and regulatory T

Question 10

what is the most important biological consequence of adaptive immunity?

Answer 10

immunological memory

Question 11

what causes swelling and other physiological changes known as inflammation?

Answer 11

substances (cytokines) like tumor necrosis factor recruit fluid, cells and molecules to the site of infection

Question 12

antibodies (B cell receptors) and T cell receptors are looking for what to bind to?

Answer 12

cognante antigen

Question 13

What cells present antigens to T cells?

Answer 13

dendritic cells, macrophages, B cells and neutrophils

Question 14

What is required for T cells to become activated?

Answer 14

antigens

Question 15

what are hormone like messengers produced by T helper cells, that communicate with other cells and affect the immune response?

Answer 15

cytokines

Question 16

what is an example of a cytokine?

Answer 16

interleukins (IL-1, IL-2…) and tumor necrosis factor

Question 17

which interleukin causes a hypothalamic fever response?

Answer 17

IL-1

Question 18

what is responsible for tissue rejection in organ transplantation?

Answer 18

Major histocompatibility proteins

Question 19

what is the function of major histocompatibility proteins?

Answer 19

function as billboards to display chopped up peptides

Question 20

Where are Class I MHC found?

Answer 20

virtually all cells of the body

Question 21

Where are Class II MHC found?

Answer 21

only on antigen presenting cells

Question 22

Which class of MHC displays what cells are producing inside?

Answer 22

Class I

Question 23

Which class of MHC displays what has been killed at battle site (external)?

Answer 23

Class II

Question 24

Class I are scanned by which cells to help kill virus infected cells?

Answer 24

Killer T cells

Question 25

Class II inform which cell about the battle?

Answer 25

T helper cells

Question 26

50-70% of circulating WBCs are?

Answer 26

Neutrophils

Question 27

Myeloid lineage consists of?

Answer 27

granulocytes and myeloid antigen-presenting cells

Question 28

name the granulocytes found within the myeloid lineage

Answer 28

neutrophils, basophils, mast cells, eosinophils

Question 29

name the myeloid antigen presenting cells within the myeloid lineage

Answer 29

monocytes (macrophages and dendritic cells)