Immune System Flashcards
What are the three groups in the immune system
Innate immunity
Adaptive immunity
Combo of both
What makes up the innate immune system
monocytes
neutrophils
eosinophils
basophils
mast cells
natural killer cells
What makes up the adaptive immune system
B&T cells or lymphocytes
What makes up the combination of both
Macrophages & Dendritic Cells
What are some hematopoietic stem cells
monocytes
neutrophils
eosinophils
basophils
mast cells
Erythrocytes
Thrombocytes
Lymphocytes (B&T)
What are some characteristics of neutrophils
poly-morpho-nuclear cells (3-5 lobes)
phagocytes & Granulocytes
acute inflammation/infection
What are the first cells to arrive at sites?
Neutrophils
What cell constitutes a major line of defense against pus- forming bacteria
neutrophils
What cells take over for neutrophils
monocytes & macrophages
What are some characteristics of monocytes
large, long-lived, bi-lobed
originate in bone marrow
infection & Inflammation
What do monocytes turn into?
macrophages
What are some characteristics of Eosinophils
involved in allergy & parasitic infections
Eosinophils take over for _____ & ________ if pathogens are too large
neutrophils and macrophages
What do esinophils release
histamine ( vasodilator)
heparin ( anticoagulant)
cytokines (inflammatory reactions)
What are some characteristics of basophils and mast cells
granulocytes involved in allergy response
What do mast cells release
Histamine
basophils and mast cells ______ the blood supply
increase
vasodilation & recruits more phagocytes to site of infection
What are the responsibilities of the erythrocytes and thrombocytes
movement and removal of antigens, antibodies, complement system
platelets- thrombosis & hemostasis
Where do B lymphocytes mature & what do they do?
Bone marrow
produce antibodies
Where so lymphocytes mature & what do they do?
Thymus
helper T cells
Cytotoxic T cells
Where do are there natural killer cells
blood & spleen
What do natural killer cells do
kill cell infected w/ virus, intracellular microbe-infected cells, and tumor cells
What is the first step in
