Immune system

Question 1

Innate immunity cells

Answer 1

Macrophages and NK cells

Question 2

Adaptive immunity types and cells

Answer 2

Cell-mediated (T cells)
Humoral (B cells and CD4 T cells)

Question 3

Immunodeficiency causes

Answer 3

HIV, drugs like long term steroid usage

Question 4

What is AIDS

Answer 4

Caused by HIV-1 lentivirus
Results in decreased CD4+ T cell numbers causing opportunistic infections, as they are involved in both cellular and hormonal immunity (secreting cytokines to induce antibody production by B cells)

Question 5

Type IV hypersensitivity

Answer 5

Cell mediated hypersensitivity, does not require antibodies
Mediated by T lymphocytes and macrophages
CD4+ T cells cause delayed type hypersensitivity by secreting cytokines that mediate inflammation, phagocytes and macrophages
CD8+ T cells cause direct cell cytotoxicity

E.g. granulomatous inflammation in TB, transplant rejection, rheumatoid arthritis, IBD