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SFM Quiz 2 > Immune signals > Flashcards

Immune signals Flashcards

1
Q

B7/CD80

A

expressed on the surface of APCs

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2
Q

CCR2 CCL2

A

analogous to IL-8 for macrophages

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3
Q

CD15 + and CD16b+

A

Found on surface of neutrophils

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4
Q

CD19 and CD21+

A

on surface of b cells

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5
Q

CD14+ (TLR4)

A

found on surface of macrophages which binds to LPS

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6
Q

CD16+ CD56+

A

On surface of NK cell

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7
Q

CD19+ CD20+

A

on surface of B cell

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8
Q

CD23

A

has high affinity acer. on surface of mast cell

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9
Q

CS23a CD23b

A

Receptor for IgE that is found on mature B cells, activated macrophages, eosinophils, basophils, dendritic cells, mast cells

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10
Q

CD25+ CD4+

A

expressed on surface of Tregs that function to inhibit self-reactive Th1 cells in periphery

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11
Q

CD3+ CD4+

A

On surface of T helper cells

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12
Q

CD3+ CD4+ CD25+ IL-10 TGF-B

A

on surface of Treg

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13
Q

CD3+

A

on the surface of all types of T cells

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14
Q

CD80

A

On dendritic cells

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15
Q

GATA-1

A

required for terminal differentiation to eryhroid lineage

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16
Q

GATA-3

A

required for development of t lymphocytes

17
Q

IFN-gamma

A

secreted by NK cells to activate macrophages

18
Q

IL-1, IL-12, IL-23

A

chemokine that call M1 macrophages to site of inflammation

19
Q

IL1, IL18

A

produced by NLRP3 inflammasome and causes potent inflammatory response. Capase-1 involvement

20
Q

IL1 TNF

A

increase expression of P and E selections on endothelium to cause “rolling leukocytes”

21
Q

IL1 TNF alpha and IL8

A

activate and call neutrophils

22
Q

IL8

A

Caller of the neutrophils

23
Q

IL10 TGFB

A

Chemokine that calls M2 macrophages to reduce inflammation

24
Q

IL10

A

Anti-inflammatory. secreted by microphones, dendritic cells, and Tregs

25
Q

IL12, IL15, Type 1 IFN

A

activate natural killer cells

26
Q

IL4 and IL5

A

important for immunological response that involve IgE and eosinophils

27
Q

IL4, IL5, IL10

A

produced by Th2 cells

28
Q

IL4

A

leads to proliferation of IgE

29
Q

IL5

A

will cause eosinophilic deletion of helminth invasion

30
Q

IL4, IL13

A

Induces monocyte to become an M2 macrophage

31
Q

IFN a

A

Interferon that inhibits viral replication by inhibition of protein synthesis. Produced by leukocytes

32
Q

INF b

A

interferon that inhibits viral replication of protein synthesis. produced by fibroblast.

33
Q

LFA 1

A

Found on neutrophils, macrophages, b cells and T cells. Binds to ICAM and is important in rolling response.

34
Q

VLA 4

A

expressed on the surface of lymphoid progenitor cell that adheres to VCAM 1. promotes about interaction between the stem cell factor and kit leading to proliferation.

SFM Quiz 2 (4 decks)

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