Immune Response Flashcards
Phagocytosis
Phagocyte attracted to pathogen by chemicals or foreign antigen
Engulfs pathogen
Bacteria in phagosome
Fuses with lysosome
Form phagolysosome Pathogen hydrolysed;
Hum oral response
Pathogen with foreign antigen detected
Engulfed by phagocyte
Antigen attached to cell membrane of phagocyte (antigen presentation)
Th cell with complementary receptor binds to antigen
Th cell stimulates B cell
Specific B cell activated
Divides to form clone (clonal selection)
By mitosis
Plasma cells produced
Release antibodies
Antibody specific to antigen
Antibody destroys cells with antigen
Cell mediated response
Pathogen with foreign antigen detected
Engulfed by phagocyte
Antigen attached to cell membrane of phagocyte (antigen presentation)
Th cell with complementary receptor binds to antigen
Activate T cell to divide
By mitosis
T cells specialize to form
• Memory cells
• Stimulate phagocytes to engulf pathogens
• Stimulate B cells to secrete antibodies.
• Activate cytotoxic T cells
Cytotoxic T cells kills infected body cells By producing porforin
Makes hoes in cell membranes.