Immune cell markers Flashcards

1
Q

T cell receptor

A

T cells (bind to antigen-MHC complex)

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2
Q

CD3

A

T cells (associated with TCR for signal transduction)

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3
Q

CD28

A

T cells (bind to B7 on APC)

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4
Q

CD4

A

Helper T cells

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5
Q

CD40L

A

Th2 Helper T cells (bind to CD40 on B cells)

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6
Q

IgD / M

A

B cells (bind to antigen)

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7
Q

CD19

A

B cells

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8
Q

CD20

A

B cells

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9
Q

CD21

A

B cells (Epstein Barr receptor)

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10
Q

CD40

A

B cells (bind to CD40L on Th2 cells)

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11
Q

MHC II

A

Macrophages, B cells, Dendritic cells (present antigen + MHC II complex to CD4 T helper cells

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12
Q

CD8

A

Cytotoxic T cells (complex with MHC I on virus cell and TCR on self)

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13
Q

B7

A

Macrophages, B cells, Dendritic cells (complex with CD28 on T helper cells to provide second signal)

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14
Q

CD14

A

Macrophages (can be activated by bacterial endotoxin/lipopolysacchrides)

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15
Q

Fc C3b receptors

A

Macrophages

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16
Q

MHC I receptor

A

NK cells

17
Q

CD16

A

NK cells (bind to Fc portion of IgG)

18
Q

CD56

A

NK cells (unique marker)

19
Q

MHC I

A

All cells, except mature RBCs

20
Q

All T cells (3)

A

TCR, CD3, CD28

21
Q

helper T cells (2)

A

CD4, CD40

22
Q

B cells (6)

A

CD19, CD20, CD21, CD40, MHC II, B7

23
Q

Macrophages (5)

A

CD14, CD40, MHC II, B7, Fc and C3b receptors

24
Q

NK cells (2)

A

CD16 (binds Fc receptor of IgG), CD 56 (unique for NK)