Immune

Question 1

Definition of AIDS

Answer 1

disorder associated with deficiency in T-cell immunity and B-cell abnormality

due HIV-1

Question 2

Clinical picture of AIDS

Answer 2

have categories ENABC

1. E
   - HIV exposed infant which do not been confirm
2. N
   - HIV exposed infant that asymptomatic
3. A
   - lymphadenopathy
   - hepatosplenomegally
   - parotitis
   - recurrent URI
   - otitis media
4. B
   - oral candidiasis
   - FTT
   - diarrhea
   - thrombocytopenia
   - cardiomyopathy
5. C
   - serious bacterial infection
   - progressive neurogenic disease
   > delay development
   > encephalopathy

• wasting syndrome
• malignant

Question 3

Diagnosis of AIDS

Answer 3

1. Clinical picture
2. Catogery E
   - serological test: ELISA
   - HIV p24 antigen detaction
   - HIV culture of blood lymphocyte

Question 4

Treatment of AIDS

Answer 4

1. Antiretroviral
   - zidovudine
   - inhibitor of HIV protease
   - lamuvidine
2. ttt of 2ry infection
3. Prophylaxis for p. carinii pneumonia
   - trimethoprim-sulfomethoxazole
4. Nutritional support