Imminity System Primer -EX2 Flashcards

1
Q

Antigen

A

Molecule that cause immune response

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2
Q

Epitope

A

Binding site for antigen

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3
Q

Pathogen

A

Disease causing agent

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4
Q

Tolerance

A

Ability to distinguish self or foreign antigen

Depends on MHC

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5
Q

Major Histocompatibility Complex

MHC

A

Act as code tags for what to attack

Code on chromosome 6

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6
Q

Classes of MHC

A

MHC I

MHC II

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7
Q

MHC I

A

Found on surface of all cells.

Acts like billboard for intercellular activity

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8
Q

MHC II

A

Made by antigen presenting cell APC

Known as macrophages, shows extra cellular abnormalities

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9
Q

Immune system cells

A

Phagocytes

Lymphocytes

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10
Q

Phagocytes-types

A

Neutrophils

Macrophages

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11
Q

Lymphocytes

-types

A

B lymphocytes

T lymphocytes

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12
Q

B lymphocytes

A

Split into plasma cell and memory cells

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13
Q

T lymphocytes

-def

A

Responsible for cell to cell response

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14
Q

T lymphocytes subgroups

A

Helper T- cd4

Memory T

Cytoxic-cd8/killer t

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15
Q

Helper T(CD4)

A

Recognize MHC II and direct response (commander)

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16
Q

Memory T

A

Long term retention and Help quicker response next time

17
Q

Cytotoxic (CD8/ killer T)

A

Recognize MHC I and destroys infected cells through perforation

18
Q

FAB (fragment antigen binding)

A

Where B cells attach to epitopes

19
Q

How antigens destroy

A

Opsonization- attract IR cells to pathogen and prepare it to get eat

Agglutination-clump cells

Activate complement -membrane attack complex (MAC)