Imm

Question 1

Autoimmune Diseases

Answer 1

• Rheumatoid Arthritis
• Systemic Lupus Erythematosus
• Hashimoto’s Thyroiditis

Question 2

Immunodeficiency Diseases

Answer 2

• AIDS

- Immunosupression due to cancer or organ transplant meds

Question 3

Hypersensitivity

Answer 3

Immune responses that are exaggerated or inappropriate for protective fxn

Question 4

Ig-E Mediated Hypersensitivity

Answer 4

Ig-E Sensitized mast cells degranulate when re-exposed to an antigen

• systemic anaphylaxis
• Hay Fever
• Asthma, Hives, Food allergies, Eczema

Question 5

Antibody-Mediates Cytotoxic Hypersensitivity

Answer 5

Antibodies directed against antigens on own individuals cells that cause lysis or destruction by NKC.

• Transfusion Rxn
• Drug-induced hemolytic anemia
• Hemolytic Disease of the Newborn

Question 6

Immune Complex-Mediated Hypersensitivity

Answer 6

Antigen-antibody complexes deposit on the cell membrane and activate complement and ensuing inflammatory response.

• Systemic Lupus Erythematosus
• Rheumatoid Arthritis
• Post-Streptococcal Glomerulonephritis

Question 7

Cell-Mediated Hypersensitivity

Answer 7

Antigen-sensitized T-cells release cytokines after being re-exposed to the antigen. Cytokines attract macrophages which release other chemical mediators & include inflammatory rxn.

• Poison Ive rxn
• Graft rejection
• TB lesions