IMI6: the immune responses against extracellular pathogens

Question 1

what are the different mechanisms pathogens develop to escape the complement system?

Answer 1

inhibitions of complement proteins or breakdown of complement proteins

Question 2

what are the different mechanisms pathogens develop to escape the PRRs?

Answer 2

disguise PAMPs or impaired the production of cytokines

Question 3

what are the different mechanisms pathogens develop to escape phagocytosis?

Answer 3

inhibition of the phagosome acidification, inhibition go the phagosome fusion with lysosome or bacteria escapes phagosome

Question 4

what are the different mechanisms pathogens develop to escape NETosis?

Answer 4

inhibition of NETosis, NET degradation or develop resistance to NETosis

Question 5

what are the different mechanisms pathogens develop to escape the MHC class II mediated antigen presentation?

Answer 5

escapes phagocytosis or degrade MHC class II

Question 6

what are the different mechanisms pathogens develop to escape the polarisation of T cells?

Answer 6

antigen variation, change to mimic self antigen or superantigens interfere with plasma cells response through impairment of T cells