Imaging Modality

Question 1

What is the definition of,

“Cerebral blood flow (CBF)”

Answer 1

Rate of delivery of metabolic substrates to tissue. (volume of blood per unit volume of tissue per unit of time, ml/100gm/min)

Question 2

What is the definition of,

“Cerebral blood volume (CBV)”

Answer 2

Volume of blood per unit weight of tissue

ml/min

Question 3

What is the definition of,

“Mean transit time (MTT)”

Answer 3

Average time for contrast to pass the vasculature in the tissue(sec) related to local perfusion pressure

Question 4

What is the definition of,

“Time to peak (TTP)”

Answer 4

Average time for contrast to reach the peak concentration in the tissue(sec)

TTP is less accurate than MTT
ก้อ วัดแค่ peak นิ →อันนี้คิดเอาเอง

Question 5

จงยกตัวอย่าง clinical implication ของ

Perfusion imaging..

Answer 5

> > Evaluate penumbra in patient cerebrovascular disease.

> > evaluate tumor perfusion in pre-/ post Rx
Eg. แยก tumor necrosis and tumor recurrent