ILCs Flashcards
1
Q
What are the cytotoxic ILCs and what are they involved in?
A
- NK cells
- Involved in immunity to viruses and cancer, and chronic inflammation
2
Q
What are the non-cytotoxic ILCs?
A
- ILC1s
- ILC2s
- ILC3s
3
Q
What are the main functions of the ILC1s?
A
- Immunity to intracellular bacteria and protozoa and chronic inflammation
4
Q
What are the main functions of the ILC2s?
A
- Immunity to helminths
- Asthma and allergic diseases
- Metabolic homeostasis
5
Q
What are the main functions of ILC3s?
A
- Lymphoid tissue development
- Intestinal homeostasis
- Immunity to extracellular bacteria
- Role in chronic inflammation
