ILA Flashcards

1
Q

Which enzyme unwids supercoiled DNA?

A

Topoisomerase

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2
Q

Where are the ribosomes assembled?

A

INSIDE the nucleus

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3
Q

Capillary occlusion is thought to occur by …

A

Endothelial damage causing multicellular (platelets, white cells) aggregates which occlude the capillary.

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4
Q

An acute pain crisis is typically caused by a capillary occlusion in the …

A

Bone

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5
Q

Sickle cell disease can be treated with hydroxyurea because it …

A

Increases the synthesis of HbF (foetal Hb), which has a greater affinity for oxygen than HbA.

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6
Q

In hypoxia, the abnormal HbS…

A

polymerises

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